A screening method called dynamic BH3 profiling can identify potentially effective combinations of existing drugs for personalised cancer therapy, research has shown.
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Triple-negative breast cancer
Two screening techniques were used by researchers to find anticancer compounds that target the aryl hydrocarbon receptor.
A new study in cell cultures has shown that the sanguinarine plant compound could be used to treat people with triple-negative breast cancer.
Studies in mice have shown that the drug ProAgio is effective at treating pancreatic cancer and triple-negative breast cancer.
A group of researchers has suggested that BBOX1 inhibitors could be used to treat triple negative breast cancer after showing success in mouse models.
Exploring how therapies with multi-faceted approaches could improve options for treatment-refractory cancers, like pancreatic and triple-negative breast cancer.
A study has shown that targeting the proteins mtp53 and PARP in triple negative breast cancer could inhibit tumour growth and provide a new treatment option.
A study has demonstrated the success of new compounds that prevent FOXM1, a transcription factor, from increasing cancer proliferation.
Researchers have discovered that a specific subset of gamma delta T cells can be found in higher numbers of breast cancer survivor tissue, indicating its role in fighting the condition.
Researchers have used whole genome sequencing to analyse breast cancers and reveal which are more responsive to treatments, which could improve the development of oncologic therapies.
A tumour-targeted CRISPR gene editing system encapsulated in a nanogel could halt the growth of triple-negative breast cancer.
A mouse study has revealed that triple-negative breast cancer could be tackled by using recombinant Tinagl1 in therapy targeting signalling pathways...
Researchers in Spain have identified a means of classifying patients with the most aggressive form of breast cancer - triple negative breast cancer; providing meaningful prognosis for the first time.
Germ line genetic testing analyses blood samples and evaluates inherited genetic changes that increase the risk of certain cancers in an individual...