news Enzyme found to be an “Achilles’ heel” in ovarian cancers 2 August 2021 | By Anna Begley (Drug Target Review) Scientists have uncovered the crucial role of the enzyme NMNAT-2 in ovarian cancers, as well as other biomarkers that could lead to treatments.
news Potential ovarian cancer treatment proves effective in pre-clinical studies 14 June 2021 | By Victoria Rees (Drug Target Review) A new radiopharmaceutical compound has shown success at treating ovarian cancer in mice and in vitro studies.
news Structure of PLEKHA7 protein domain imaged, presenting cancer drug target 22 April 2021 | By Victoria Rees (Drug Target Review) A range of imaging and computational techniques were used by researchers to discover the structure of the PH domain of PLEKHA7.
news Possible method to apply CAR T-cell therapy to solid tumours developed 19 March 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a CAR T-cell engineering technique to ensure that only cancer cells are targeted, leaving healthy cells alone in solid tumours.
news LEAP proton therapy could target cancer cells that resist treatment 18 February 2021 | By Victoria Rees (Drug Target Review) A proton therapy that targets cancer cells which are resistant to treatment has shown success, sparing surrounding healthy cells.
news Study provides insight into muscle wasting in cancer patients 4 February 2021 | By Victoria Rees (Drug Target Review) Using a mouse model, researchers found that cancer progression led to fewer skeletal muscle ribosomes, likely explaining muscle wasting.
news Cancer-killing virus could improve precision medicine 2 December 2020 | By Victoria Rees (Drug Target Review) A new cancer-killing virus called CF33 has shown success in pre-clinical trials, helping the immune system to eradicate tumours.
news CRISPR-based treatment successfully targets glioblastoma and ovarian cancers in vivo 19 November 2020 | By Hannah Balfour (Drug Target Review) Researchers say this is the first time that CRISPR-Cas9 gene editing has been used to treat cancer effectively in a living animal and that the technique could be revolutionary.
news Novel tumour spheroids could improve ovarian cancer treatments 5 October 2020 | By Hannah Balfour (Drug Target Review) Researchers have developed a new self-assembling three-dimensional (3D) ovarian cancer tumour model to recreate the in vitro disease more accurately.
news Drug compound used to overcome chemotherapy resistance in mice 17 April 2020 | By Victoria Rees (Drug Target Review) Researchers testing 2-deoxy-D-glucose in mouse models of ovarian cancer report that the compound significantly improves the effectiveness of the chemotherapy drug, carboplatin.
news Removing macrophages shows success against ovarian cancer in mice 27 March 2020 | By Victoria Rees (Drug Target Review) By removing two kinds of macrophages in mice, researchers showed that ovarian tumours in mice were reduced in size and stopped spreading.
news Novel palladium compound shows potent action against treatment resistant cancer cells 29 January 2020 | By Hannah Balfour (Drug Target Review) Research demonstrated a complex of palladium and thiosemicarbazone is a more selective and powerful chemotherapeutic than the current standard of care cisplatin.
news Extensive tumour protein analysis reveals new therapy targets 16 December 2019 | By Hannah Balfour (Drug Target Review) New research has categorised hundreds of cancers based on their common protein mutations, highlighting cell components and tumour microenvironments as possible new therapy targets.
news Promising drug developed for ovarian and pancreatic cancers 22 July 2019 | By Drug Target Review An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.
news Intriguing egg protein behaviour may shape fertility and cancer treatment 30 October 2018 | By Drug Target Review Scientists in the U.S. have published their findings about the behaviour of proteins in mouse eggs, projecting possible impacts on infertility and cancer treatment.
![Ovarian cancer cells forming a cancer spheroid as they grow within the peptide-protein co-assembling material [Credit: Alvaro Mata].](https://drug.russellpublishing.co.uk/wp-content/uploads/ovarian-cancer-spheroid-3D-model-750x500.jpg)
![Ovarian cancer cells forming a cancer spheroid as they grow within the peptide-protein co-assembling material [Credit: Alvaro Mata].](https://drug.russellpublishing.co.uk/wp-content/uploads/ovarian-cancer-spheroid-3D-model-e1601896830935.jpg)
