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medulloblastoma

cartoon image of a brain with a large red ball inside representing a tumour

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ABCC4 transporter could be a novel target for paediatric medulloblastoma treatments

2 April 2020 | By Hannah Balfour (Drug Target Review)

Researchers demonstrated that ABCC4 is essential to signalling in the SHH subgroup of medulloblastomas and when expression was reduced in mice, the tumours shrank.

news

Organoids produced to help develop paediatric brain tumour treatments

30 January 2020 | By Hannah Balfour (Drug Target Review)

Scientists have produced hundreds of organoids which they say could be produced on a large-scale as a low-cost tissue model to help research and test new medulloblastoma therapies.

New weakness found in most common childhood malignant brain tumour

news

New weakness found in most common childhood malignant brain tumour

7 December 2017 | By Drug Target Review

A new weakness found in medulloblastoma could lead to more personalised medicine and improved treatment for some patients.

news

Sonic Hedgehog pathway identified as a target against medulloblastoma

2 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers raise hopes for developing a combination targeted therapy to treat medulloblastoma and other tumours...

news

Researchers identify a key controller of biological machinery in cell’s ‘antenna’

8 June 2017 | By Niamh Marriott (Drug Target Review)

St. Jude Children’s Research Hospital discovery of a regulatory enzyme working at the primary cilium could lead to treatments for the brain tumour medulloblastoma.

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Recommended

medulloblastoma

ABCC4 transporter could be a novel target for paediatric medulloblastoma treatments

Organoids produced to help develop paediatric brain tumour treatments

New weakness found in most common childhood malignant brain tumour

Sonic Hedgehog pathway identified as a target against medulloblastoma

Researchers identify a key controller of biological machinery in cell’s ‘antenna’