news Researchers simulate hepatitis B infection using computational method 8 September 2021 | By Anna Begley (Drug Target Review) The new study modelled the process of capsid disassembly of the hepatitis B virus at an atomic level to help develop targeted therapies.
article The development of biomaterial-based vaccine platforms against viruses 31 March 2021 | By Dr Kaushik Chatterjee (Indian Institute of Science), Dr Sonal Asthana (Indian Institute of Science), Dr Sushma Kumari (Indian Institute of Science) Recent years have seen an increase in the development of biomaterial and nanoparticle-based vaccine formulations. Sushma Kumari, Sonal Asthana and Kaushik Chatterjee from the Department of Materials Engineering at the Indian Institute of Science discuss why these materials have such high potential in the fight against infectious diseases.
article What we know about COVID-19 and the inflammatory response 10 March 2021 | By Sadya Arnett (Scientific Writer) A year on from discovering COVID-19 we are starting to understand why some people suffer more severely after infection. Sadya Arnett discusses recent research into the interconnection between host inflammation and SARS-CoV-2.
article Human 3D cell-based systems to research gout: drug discovery for a neglected disease 18 December 2020 | By Hannah Balfour (Drug Target Review) In this article Andrew Nyborg from Horizon Therapeutics discusses why researchers are taking a second look at gout and how they are modelling the condition, which is unique to humans.
news 2020 Nobel Prize goes to discoverers of hepatitis C 6 October 2020 | By Hannah Balfour (Drug Target Review) The 2020 Nobel Prize in Physiology or Medicine has been bestowed upon researchers who helped identify the hepatitis C virus in the 1970s.
news Study identifies eight novel coronavirus replication terminators 6 July 2020 | By Hannah Balfour (Drug Target Review) Scientists reveal eight new molecules, five of which are already US FDA-approved, that can block the polymerase reaction SARS-CoV-2 uses to replicate its genome.
news Could T-cell immunotherapy be the answer to COVID-19? 22 April 2020 | By Victoria Rees (Drug Target Review) Scientists from Singapore have argued that T-cell immunotherapy can be used to combat a range of infectious diseases, including COVID-19.
news Proteins vital for hepatitis B infection discovered by researchers 10 March 2020 | By Victoria Rees (Drug Target Review) A new study has revealed five factors and proteins that hepatitis B infection needs for replication of its DNA, providing insight into the disease.
article Discovering how drugs combat HIV and why resistance can occur 17 February 2020 | By Victoria Rees (Drug Target Review) A group of researchers, led by Professor Zucai Suo, have revealed the mode of action of two HIV drugs and identified how resistance can develop, which they say could lead to improved drug design in the future.
news Sensitive new assay detects hepatitis B infection in single liver cells and serum 12 April 2018 | By Dr Zara Kassam (Drug Target Review) Technique measuring the cccDNA marker may allow earlier detection of hepatocellular carcinoma in patients...
news CpAM molecules advance fight against hepatitis B 9 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer...
news AiCuris’ preclinical Hepatitis B study gains NIH support 28 November 2016 | By Niamh Louise Marriott, Digital Editor This preclinical study should explore the potential of AIC649 to cure infections caused by hepatitis B virus (HBV) and is investigating the efficacy...
news AIC649 shows potential to induce functional cure in preclinical HBV study 5 January 2016 | By Victoria White AIC649 is an inactivated parapoxvirus ovis particle preparation with distinct immunological activities including regulated cytokine release and activation of T-cell responses...
article Novel approaches to targeting protein tyrosine kinases 10 June 2015 | By Carol Trim (Canterbury Christ Church University), Danielle McCullough (Canterbury Christ Church University) Protein kinases, a diverse group of cellular enzymes, play fundamental roles in maintaining normal cellular functions such as growth, cell cycle control, proliferation, differentiation, migration, cellular survival and apoptotic induction.
news Partnering for Cure programme announces new winning projects designed to investigate novel ways to cure viral diseases 13 November 2014 | By Bristol-Myers Squibb The Partnering for Cure faculty of experts announced the four recipients of awards for research proposals that will help to provide insights into the pathophysiology of viral diseases and the potential development of cure strategies in HIV, hepatitis B (HBV) and hepatitis C (HCV)...
