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A genetic approach to high insulin levels
A team of researchers have succeeded in precisely describing the effects of a frequent genetic mutation in cases of congenital hyperinsulinism...
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Diabetes
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New technology could predict the risk of type 2 diabetes
Researchers have announced a new technology-based approach that could lead to a more accurate identification of type 2 diabetes...
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Nanoparticles give disease-fighting properties to cells
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
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New marker could refine the process of producing hPSC-derived insulin cells
Scientists at the University of Copenhagen have identified a unique cell surface protein present on human pancreatic precursor cells providing for the first time a molecular handle to purify the cells whose fate is to become cells of the pancreas - including insulin producing cells.
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New research highlights key differences between mice and men
Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs that have worked in animal experiments are not equally successful in humans. The researchers discovered differences – as well as hitherto unknown similarities – in the function of insulin-producing beta cells.
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£22m fundraise targeted for innovative diabetes monitoring platform
Radisens Diagnostics, an Irish medtech business, is aiming to raise £22 million to bring its innovative diabetes management platform to market...
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New WHO Collaborating Centre for Physical Activity and Health
The University of Zurich is launching a new WHO Collaborating Centre for Physical Activity and Health. The Physical Activity and Health Unit and other groups of the Epidemiology, Biostatistics and Prevention Institute will support the Physical Activity Strategy for the World Health Organization (WHO) European Region.
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Newly discovered disease mechanism for type 2 diabetes
A newly discovered mechanism behind reduced insulin production in type 2 diabetes is now being presented.
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Diabetes drug prevents cardiovascular disease in obese mouse study
A study by researchers at the University of Missouri School of Medicine found that the diabetes medication linagliptin can protect against stiffening of the left ventricle of the heart in overweight female mice. The finding may have implications for management of cardiovascular disease in humans.
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The gut microbiota plays key role in diabetes treatment
A clearer picture of how the classic diabetes medication metformin works has emerged.
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Blood marker can predict heart disease risk in type-2 diabetes patients
Measuring a blood marker, copeptin, can successfully predict the risk of heart attacks in people with type-2 diabetes.
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Exscientia to collaborate with Sanofi for EUR250mil multiple-product development
Exscientia has agreed a strategic research collaboration, and licence option agreement with Sanofi in the high-interest area of metabolic disease.
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Pathways leading to beta cell division identified, may aid diabetes treatment
Pancreatic beta cells help maintain normal blood glucose levels by producing the hormone insulin -- the master regulator of energy (glucose). Impairment and the loss of beta cells interrupts insulin production, leading to type 1 and 2 diabetes.
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Premature cell differentiation leads to disorders in pancreatic development
Neonatal diabetes mellitus (NDM), or diabetes among infants less than six months of age, is a rare form of diabetes caused by a mutation in genes crusial to the development or function of beta cells. In about half of such cases, the disease becomes permanent (PNDM). Mutations in more than…
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3D visualisation of the pancreas – new tool in diabetes research
Umeå researchers have created datasets that map the three-dimensional distribution and volume of the insulin-producing cells in the pancreas.
