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27 November 2020 | By Dr Pushpanathan Muthuirulan (Harvard University)
In October this year, Emmanuelle Charpentier and Jennifer Doudna, the two scientists who pioneered the revolutionary gene-editing technology CRISPR, were awarded the Nobel Prize in Chemistry. Here, Pushpanathan Muthuirulan discusses the potential for this technology and the importance of using it safely, ethically and responsibly.
21 February 2019 | By Drug Target Review
Gene therapy has been used to restore hearing in an adult mouse model of DFNB9 deafness, one of the most frequent cases of congenital genetic deafness...
3 July 2018 | By Drug Target Review
A small-molecule drug is one of the first to preserve hearing in a mouse model of an inherited form of progressive human deafness, report investigators at the University of Iowa, Iowa City, and the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders (NIDCD).
20 December 2017 | By Steve Bremer (Drug Target Review)
Researchers use CRISPR-Cas9 to target a mutation in the Tmc1 gene that causes the loss of hair cells in the inner ear.
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