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New models for intranasal drug delivery
In this article, Dr Jon Volmer and Dr Jon Lenn discuss a new approach to formulation models to test drug delivery based on reconstituted nasal epithelium.
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Chronic obstructive pulmonary disease (COPD)
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New inhaled therapy could treat deadly impacts of asthma
Scientists have developed an inhaled treatment for asthma that prevents excess mucus from building up in mice.
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Novel bronchodilator could be used for control of asthma
Study identifies a promising new compound that can open constricted airways and could be a promising treatment for obstructive lung diseases.
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Novel therapeutic approach shows promise in mice with COPD
By blocking the lymphotoxin beta receptor signalling pathway, researchers were able to prevent COPD progression and induce a full restoration of lung tissue.
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Stem cells in COPD patient lungs revealed as drug target for condition
There are heightened levels of abnormal stem cells in the lungs of COPD patients, presenting a drug target that researchers are screening compounds against.
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Machine learning could improve tissue model purity
An innovation using artificial intelligence to analyse developing lung cell developments in vitro revealed what promotes them to develop and allowed researchers to create better quality lung tissue models.
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New study offers insights on genetic indicators of COPD risk
Researchers have discovered that genetic variations in the anatomy of the lungs could serve as indicators to help identify people who are particularly at risk for COPD...
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Therapy proves effective in subgroup of COPD patients
An antibody treatment has been found to reduce the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant COPD...
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Hamish Ryder joins Drug Target Review Advisory Board
Prior to joining CRT-DL, Dr Ryder held positions in pharmaceutical and biotech companies for over 20 years ...
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Lung cancer screening could save money as well as lives, research shows
Lung cancer screening is likely to be cost-effective, particularly if it also identifies other tobacco-related conditions in high-risk people, suggests new research.
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Study shows potential of stem cell therapy to repair lung damage
A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Although, still at a pre-clinical stage, these findings have important potential implications for the future treatment of patients.
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Sound Pharmaceuticals receives $1.6 Million Award to treat CF-related tinnitus
Sound Pharmaceuticals has been awarded up to $1.6M from Cystic Fibrosis Foundation Therapeutics (CFFT), the non-profit drug discovery and development affiliate of the Cystic Fibrosis Foundation.
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AstraZeneca provide insight into biomarkers and personalised treatment at Asthma & COPD 2017
SMi’s 13th annual Asthma & COPD conference returns to London on the 29 and 30 March 2017...
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MRC Technology, AstraZeneca, Asthma UK and British Lung Foundation to collaborate on respiratory disease research
1 September 2016 | By Niamh Louise Marriott, Digital Content Producer
A collaboration to investigate the link between epigenetics and respiratory disease and to find new drug treatments involves...
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New initiative to find epigenetic drug targets in respiratory disease
15 June 2016 | By Victoria White, Digital Content Producer
MRCT and AstraZeneca are seeking academics with relevant epigenetics targets to collaborate with them to develop novel treatments for respiratory diseases...