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Largest genome sequencing project launched in UK
The UK Biobank, the world’s largest genetics project, will sequence 500,000 genetic samples, which will be available to researchers everywhere.
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Inflammatory regulator molecule identified by study
Researchers have discovered an enzyme that is pivotal in deciding whether cells survive or die in inflammatory diseases, so provides a drug target.
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New biological targets could lead to therapies for drug-resistant cancers
A study on how Polycombs regulate cellular identity could lead to alternative treatments for patients with drug-resistant cancer.
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Molecule discovered that regulates development of tumours
Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
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Researchers reverse obesity in mice using CRISPR-Cas9
A study has used CRISPR-Cas9 to treat obesity and type 2 diabetes symptoms in mice, highlighting the potential use in humans.
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Structure of crucial metabolic enzyme revealed by high-end microscopy
Scientists reveal the atomic structure and regulative mechanism of the metabolic enzyme transhydrogenase.
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Blocking new protein helps immune system to fight cancer
A protein discovery could lead to a new and highly potent immune-therapeutic drug for the eradication of cancers using natural killer cells.
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Telomere damage in cells is caused by runaway mitochondria
Using new technology researchers have shown that sick mitochondria pollute the cells they are supposed to be supplying with power.
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Study uncovers key processes behind MYC cancer gene
Researchers have discovered that MYC cancers use the cell’s machinery to make lipids and identified a lipid signature, which could be exploited in the development of new therapies.
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Researchers image structure of cancer metastasis target
The structure of a key receptor involved in tumour metastasis has been imaged in a study, providing opportunities to develop cancer treatments.
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Genes responsible for gender differences in tumours identified
A new study has identified possible regulators that determine differences in cancer tumours between genders.
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‘Ubiquitin clipping’ proteomics technique could be used as novel treatment
A new technique called ‘ubiquitin clipping’ has been created which could aid proteomics research and the development of new drugs for ubiquitination.
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Interferon pathway could provide drug target for cancers
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
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Protective protein guards against DNA damage
It has been discovered that Polo-like kinase (PLK1) guards against severe DNA damage and could help target fast-growing cancer cells.
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Study reveals cancer cell fuelling mechanism
Researchers have identified the process behind cancer cell energy production, providing a drug target for treatments to inhibit growth.
