![A microscopy image of Leptospira bacteria [Credit: Wunder et al. (CC BY 4.0)].](https://drug.russellpublishing.co.uk/wp-content/uploads/Leptospira-bacteria.jpg)
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Attenuated vaccine could combat fatal Leptospira bacteria
A single vaccination with a mutated Leptospira bacteria prevented rodent models from developing leptospirosis, the most fatal type of zoonotic disease worldwide.
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![Wasp on a wooden platform [Credit: University of Pennsylvania].](https://drug.russellpublishing.co.uk/wp-content/uploads/Vespula-lewisii-wasp-750x500.jpg)
![Wasp on a wooden platform [Credit: University of Pennsylvania].](https://drug.russellpublishing.co.uk/wp-content/uploads/Vespula-lewisii-wasp-e1602594547599.jpg)
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Novel antimicrobial molecules derived from wasp venom
Altering the mastoparan-L (mast-L) peptide found in Vespula lewisii wasp venom, researchers created several novel antimicrobial molecules.
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Researchers uncover drivers of memory B cell formation
The team demonstrated that expression of Bach2 protein and reduced mTORC1 activity is necessary for germinal B cells to become memory B cells.
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Novel GI tract coating could deliver drugs, aid digestion or control obesity
The developers of a temporary coating which adheres to the small intestine demonstrated it could be modified to deliver drugs, aid digestion and stop absorption of glucose.
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Novel tuberculosis transport protein could be target of new treatments
Cryogenic electron microscopy revealed that the vitamin B12 transporter on Mycobacterium tuberculosis acts like a non-selective sluice, transporting both the vitamin and antibiotics.
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Cannabidiol identified as potential ‘helper’ compound for antibiotics
Researchers have found that using antibiotics in combination with cannabidiol (CBD) enhanced their effect against Staphylococcus aureus bacteria.
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CRISPR-Cas3 used to combat C. difficile in lab and mice
Researchers have shown that CRISPR-Cas3 can successfully attack C. difficile in vitro and in mice, by causing DNA damage to the pathogen.
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Blocking bacterial competence could prevent antibiotic resistance
Scientists suggest competence-blocking, ‘anti-evolution’ drugs could be administered alongside antibiotics to prolong the period before bacterial resistance emerges.
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Novel antibody breaks bacterial biofilms and prevents sepsis in mice
A new monoclonal antibody has been discovered which disassociates bacterial biofilms and stops bacteria from entering into circulation has been tested in mice.
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Metal-containing compounds could lead to new antibacterials
International collaboration has shown that compounds with metals in them show antibacterial activity against MRSA, E. coli and A. baumannii.
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Study reveals how immune system handles fungal and viral infections
Researchers have studied how the human body responds to viral infection when already infected by fungi, offering insights into the immune system.
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New T-cell discovery could lead to treatments for both bacterial infections and autoimmune conditions
A novel highly activated form of T cells could be suppressed to treat autoimmune conditions and activated in treating bacterial infections.
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Secret life of antimicrobial peptide revealed through CRISPR
Antimicrobial peptides were found to act against Gram-negative bacteria and certain fungi by working either together or by adding up their individual effects...
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Peptide research gives insight on tackling bacteria
Researchers have paved the path towards redesigning antibiotics through the alteration of the peptide assembly involved in the process...
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Naturally occurring potent antibiotic revealed
A natural antibiotic was found to be made from an enzyme, through it triggering chemical reactions that help the production of the bacterial toxin...
