news Brain organoids mimic autism-related head size changes 30 August 2021 | By Anna Begley (Drug Target Review) Scientists have developed brain organoids that recapitulate the head size of autism patients to study the condition as well as possible therapies.
news Team reveals miR-29 as regulator of processes for normal brain maturation 7 April 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that miR-29 can control brain maturation in mammals, presenting a target for autism, epilepsy and other conditions.
news Role of enzyme in reactivating neural stem cells in models identified 12 February 2021 | By Victoria Rees (Drug Target Review) An enzyme in fruit fly larvae plays a role in reactivating neural stem cells, which could explain how some neurodevelopmental disorders occur.
news Key modifier identified in genetic deletion related to autism 18 February 2020 | By Rachael Harper (Drug Target Review) A key modifier has been identified by researchers in a large fruit fly genetic deletion related to neurodevelopmental disorders such as schizophrenia and autism.
news Novel therapeutic strategy reverses autism symptoms in mice 22 October 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered a pathway that causes behavioural abnormalities and other hallmarks of autism; they also revealed how to silence this and reverse the symptoms in mice.
news Scientists discover unique imaging technique to view synapse proteins 27 September 2019 | By Drug Target Review Researchers in the US have devised a new way to clearly image proteins located in synapses, which they hope will faciliate future treatment for diseases associated with blocked gene expression.
news Early treatment could reverse autistic behaviour in tuberous sclerosis 10 October 2018 | By Drug Target Review Scientists may have found a sensitive time period where autism related social deficits could be reversed in tuberous sclerosis...
news Developments in EEG brain scans could detect mental disorders early 26 September 2018 | By Iqra Farooq (Drug Target Review) Researchers at the University of San Francisco have suggested how advances in EEG brain scanners could help to diagnose brain conditions earlier...
news Protein ‘trafficker’ provides insight into autism 24 September 2018 | By Iqra Farooq (Drug Target Review) The protein ASTN2 has been identified as a trafficking protein that ushers proteins away from the membrane ready for degradation in the cell...
news New biomarker panel could accelerate autism diagnoses 17 September 2018 | By Drug Target Review Researchers have identified a group of blood metabolites that could help detect some children with autism spectrum disorder (ASD)...
news CRISPR-Gold used to reduce repetitive behaviours in FXS 26 June 2018 | By Drug Target Review Gold nanoparticles carried Cas9 enzyme into brain, editing receptor and lessening burying behaviour...
news Link found between neurotransmitter imbalance and brain connectivity in those with autism 11 June 2018 | By Drug Target Review Researchers have identified a link between a neurotransmitter imbalance and brain connectivity between regions of the brain that play a role in social communication and language.
news Scientists find possible autism biomarker in cerebrospinal fluid 3 May 2018 | By Drug Target Review Researchers have found that low vasopressin in the cerebrospinal fluid may be a biomarker for autism...
news Helpful B cells lend a hand to developing neurons 16 March 2018 | By Drug Target Review Researchers at Osaka University have identified an immune cell that promotes the growth of neuron-supporting cells in the developing mouse brain.
news Autism risk factor search aided by epigenetics study 17 January 2018 | By Drug Target Review Scientists have identified more than 2,000 regulatory regions involved in learning that correlate strongly with autism, suggesting future focus for autism research.