article New models for intranasal drug delivery 6 August 2021 | By Dr Jon Lenn (MedPharm), Dr Jon Volmer (MedPharm) In this article, Dr Jon Volmer and Dr Jon Lenn discuss a new approach to formulation models to test drug delivery based on reconstituted nasal epithelium.
news Asthma vaccine shows success in pre-clinical studies 18 May 2021 | By Victoria Rees (Drug Target Review) A new conjugate vaccine has shown promise at protecting mice against the effects of cytokines associated with asthma.
news Two novel molecules to potentially combat asthma discovered 26 January 2021 | By Victoria Rees (Drug Target Review) Researchers have discovered that giving L-tyrosine and PCS to mice prevents lung inflammation and an allergic asthma response.
news New inhaled therapy could treat deadly impacts of asthma 14 January 2021 | By Victoria Rees (Drug Target Review) Scientists have developed an inhaled treatment for asthma that prevents excess mucus from building up in mice.
news Novel bronchodilator could be used for control of asthma 5 January 2021 | By Hannah Balfour (Drug Target Review) Study identifies a promising new compound that can open constricted airways and could be a promising treatment for obstructive lung diseases.
article Unlocking the power of the microbiome in life sciences R&D 23 December 2020 | By Anthony Finbow (Eagle Genomics) Anthony Finbow explains how applying microbiome-based evidence to disease modelling will enable researchers to devise more targeted treatments.
news Mystery glycoprotein could prevent respiratory distress 18 September 2020 | By Hannah Balfour (Drug Target Review) According to researchers, the DMBT1S8 molecule can halt inflammation in the respiratory tract through its interaction with the Siglec-8 receptor on immune cells.
news Tregs produced by mesenchymal stromal cells with novel technique 1 May 2020 | By Victoria Rees (Drug Target Review) By culturing blood cells with mesenchymal stromal cells (MSCs), researchers induced the production of cells with the same functionality as Tregs.
news Larval protein could suppress inflammatory reactions, say researchers 27 April 2020 | By Victoria Rees (Drug Target Review) A study has revealed that a protein of roundworm larvae which needs to invade the intestines of rodents to survive could be used to control inflammation.
article Safer and more affordable medicine for all? How pharmacogenomics may level the playing field 16 March 2020 | By Drug Target Review Dr Mike Tocci discusses how pharmacogenomics can revolutionise medical research and improve the efficacy and quality of drugs.
news Asthma patient genetic analyses reveals glucocorticoid resistance mutation 14 January 2020 | By Victoria Rees (Drug Target Review) A genetic analysis has shown that a mutation in the HSD3B1 gene is connected to glucocorticoid treatment resistance in patients with severe asthma.
news Protein vital for enterovirus replication identified by study 17 September 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered a particular protein that is required for enterovirus replication and survival, presenting a therapeutic target.
news Researchers discover bronchospasms mechanisms using microdevice 26 August 2019 | By Victoria Rees (Drug Target Review) A ‘bronchi-on-a-chip’ has been created by researchers to identify the processes of bronchospasms which could aid in respiratory disease therapies.
news Integrated multi-‘omic’ studies could lead to precision treatment for asthma 3 July 2019 | By Drug Target Review Researchers say integrated multi-'omic' studies could accelerate the use of precision medicine for asthma patients.
news Study reveals vulnerability of common pathogenic viruses 13 June 2019 | By Victoria Rees (Drug Target Review) Researchers have developed a stabilisation technique for widespread viruses, creating drug opportunity.
