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Refreshing how we approach neuroscience with a novel screening technology
Drug Target Review discusses how NETSseq, a novel profiling technology, is bringing new insights to neurodegenerative and psychiatric diseases.
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Amyotrophic Lateral Sclerosis (ALS)
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L-serine could be used to treat ALS, after promising results in primate study
Researchers have shown that, when treated with L-serine, a non-human primate model of ALS had fewer pathologies associated with the disease.
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Gene found to protect motor neurons against degeneration
Results of an international collaboration show promise for the future of motor neurone disease treatment efforts, as protective gene is identified.
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Astrocytes could be harnessed to protect motor neurons in MND
Scientists using a new motor neuron disease (MND) model have shown astrocytes may protect neurons from toxic TDP-43 protein aggregates in the early stages of disease.
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Screening platform reveals compounds that protect neuronal mitochondria
Researchers have developed a screening system and identified a set of compounds that protect neuronal mitochondria in mice.
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The implication of a dysfunctional proteasome regulator in neurodegenerative disease
Disrupted protein homeostasis from PI31 inactivation may initiate the process of neurodegeneration seen in Alzheimer’s, ALS and other similar diseases, says new research.
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ALS pathological mediator identified by researchers
A potential target for ALS has been revealed by a study which found the Fos-B gene encouraged axonal branching.
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Motor neuron disease electrical signalling pathways mapped
A study has used EEG to investigate the neuron networks that act abnormally in the condition, providing a significant step in the search for treatments.
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US company put on notice for marketing unapproved stem cell products
Arizona company claims their products can treat Lyme disease, diabetes, Parkinson’s disease and more, but have not been approved for any use.
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Potential therapeutic target for ALS revealed
Strathmin2 could be used as a biomarker for amyotrophic lateral sclerosis (ALS), a debilitating condition with no proper diagnostic tests or treatments...
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New tools accurately illuminates intracellular phase separation
Researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells...
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Drugs in development for cancer may also fight brain diseases
PARP inhibitors show promise in preventing toxic accumulations of brain disease proteins in Penn research study...
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New drug for ALS ready for clinical trials
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
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Changes to specific MicroRNA involved in development of Lou Gehrig’s disease
A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS).
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Antibodies protect nerve-muscle connections in Lou Gehrig’s disease
A study identifies a novel treatment strategy that preserved neuromuscular synapses in a mouse model of aggressive ALS...
