Five of the most recent microscopy developments 23 July 2020 | By Victoria Rees (Drug Target Review) Drug Target Review highlights five of the latest imaging advancements in the field of microscopy.
Revealing the genetic signature of neurodegenerative disease 21 July 2020 | By Hannah Balfour (Drug Target Review) Which immune cells contribute towards immune-induced neurodegeneration and how could this knowledge enable conditions such Alzheimer’s and multiple sclerosis to be treated?
Drug side effects: an open source tool to predict adverse reactions 14 July 2020 | By Victoria Rees (Drug Target Review) Researchers who developed a machine learning algorithm to predict the adverse effects of new drug compounds have released it as an open source tool.
Prophylactics for COVID-19 – known and unknown 9 July 2020 | By Alan Olan This article outlines the ideal scientific research that should be conducted to design a prophylactic to combat COVID-19.
The hope of rejuvenation: using plasma to reverse ageing in mice 8 July 2020 | By Victoria Rees (Drug Target Review) Researchers have found that a plasma exchange process can act as a molecular reset button for old blood, improving the health of ageing mice.
From inception to conclusion: how digitalisation is impacting drug development 3 July 2020 | By Phoebe Chubb (freelance author) Phoebe Chubb explores how digitalisation is shaking up the world of drug discovery and development by increasing productivity and reducing human error.
The coronavirus: seasonality and host-specific action of a “sexy” killer 2 July 2020 | By Dr Ulrich Kutschera (University of Kassel) Dr Ulrich Kutschera outlines why more studies are necessary before the spread and deadliness of the novel coronavirus is fully understood.
Unlocking the power of machine learning for small molecule drug discovery 30 June 2020 | By Victoria Rees (Drug Target Review) Rick Wagner of ZebiAI and Patrick Riley of Google Accelerated Science (GAS) discuss the development and benefits of a new machine learning drug discovery platform.
Targeting SARM1 to protect vision across retinal degenerative diseases 23 June 2020 | By Dr Ema Ozaki (Trinity College Dublin), Dr Sarah Doyle (Trinity College Dublin) Dr Sarah Doyle and Dr Ema Ozaki outline their research into SARM1 and why it presents an attractive target for treating retinal degeneration.
3D bioprinting COVID-19 lung models for drug development 19 June 2020 | By Hannah Balfour (Drug Target Review) Keith Murphy, CEO of Viscient Biosciences, discusses the process of developing a 3D bioprinted tissue model and their potential in developing therapeutics for COVID-19 and other diseases.
Why are women underrepresented in COVID-19 research authorship? 17 June 2020 | By Victoria Rees (Drug Target Review) An analysis of papers relating to COVID-19 has found that female researchers make up a third of authors. Here, the potential reasons behind this figure are explored and a possible solution to encourage equality.
What immuno-oncology research can tell us about COVID-19 11 June 2020 | By Dr Jing Watnick (Vigeo Therapeutics) Dr Jing Watnick discusses how lessons learnt from cancer immunotherapy treatments could be applied to the development of COVID-19 therapies.
Antibody library screening: high throughput strategies 10 June 2020 | By Emma Cummins - Centre for Drug Research and Development Canada, Gregorio Aversa - Abimmune Technologies Inc., Ismael Samudio - Centre for Drug Research and Development Canada As the number of antibody discovery platforms and formats expands, various characteristics must be rigorously screened for and taken into consideration when deciding which hits to progress to successful development. The earlier in the antibody discovery pathway the assessment is carried out, the greater the hit enrichment and selection will…
TMPRSS2 inhibitors, Bromhexine, Aprotinin, Camostat and Nafamostat as potential treatments for COVID-19 4 June 2020 | By Arsalan Azimi (Shiraz University of Medical Sciences) Arsalan Azimi explains why inhibiting TMPRSS2 with clinically proven protease blockers could work as a therapeutic strategy against COVID-19.
The effect of temperature and humidity on the number of cases and deaths of COVID-19 all over the world 4 June 2020 | By Sarah Ahmed (Kolabtree) Sarah Ahmed explores how environmental factors may be causing the disparity in numbers of cases between different countries.
