Application Note: ATPlite assay performance in human primary cells
Posted: 18 July 2018 | Verena Brucklacher-Waldert (Crescendo Biologics) | No comments yet
ATPliteTM and ATPlite 1step are robust, rapid, high-throughput luminescence assays used to assess a compound’s druggability.
One of the criteria for a compound to be considered druggable is the ability to cause or block a biological activity without toxic effects in an in vitro setting using primary human cells. As a read-out for compound-induced activity or toxicity, it is common to determine cell proliferation or cell death. Proliferation and cytotoxicity can be by looking at ATP levels in the cell.
See how ATPlite and ATPlite 1step serve as robust, rapid, high-throughput luminescence assays to quantitatively evaluate proliferation and cytotoxicity in culture human primary cells.
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