Whitepaper: Accelerating Gαq GPCR Drug Discovery with recognized and reliable tool

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Posted: 26 September 2016 | Cisbio Bioassays | No comments yet

Accelerating-Gαq-GPCR-Drug-Discovery-with-recognized-and-reliable-tool-–-exclusive-whitepaper

Cisbio Bioassays has developed a GPCR platform based on the company’s HTRF® technology to measure second messenger accumulation…

This platform includes IP-One, a very unique, non-isotopic assay. Over the past decade IP-One has repeatedly demonstrated its efficacy for discovering and/or characterizing new compounds targeting GPCRs. IP-One is a reliable and recognized tool for investigating the Gαq/11 coupled receptor.

IP-One assays detect the accumulation of inositol monophosphate, a stable downstream metabolite of IP3 induced by the activation of a phospholipase C (PLC) cascade.

Download your exclusive IP-One eBook and find why IP-One will:

Precisely identify Gq drug targeted candidates
Reduce your false positive and negative rate
Obtain more pharmacologically relevant lead molecules
Ensure to have a pinpoint signal specificity

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Whitepaper: Accelerating Gαq GPCR Drug Discovery with recognized and reliable tool

Download your exclusive IP-One eBook and find why IP-One will:

This whitepaper is restricted - login or subscribe free to access

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Whitepaper: Accelerating Gαq GPCR Drug Discovery with recognized and reliable tool

Download your exclusive IP-One eBook and find why IP-One will:

This whitepaper is restricted - login or subscribe free to access

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