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Novel vaccine protects mice against Staphylococcus aureus infection, say researchers
The novel vaccine 4X-SA-GP harnesses the anti-fungal immune response to provide immunity against Staphylococcus aureus (S. aureus) infection.
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COVID-19 vaccine elicits high levels of neutralising antibodies in mice
A potential COVID-19 vaccine, made from a modified vesicular stomatitis virus with the SARS-CoV-2 Spike protein, was shown to protect mice against the virus.
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Potential COVID-19 treatment and vaccine combination shows success in cells
A possible treatment and vaccine combination for COVID-19 has shown positive results in pre-clinical studies using human cells.
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Atomic-scale details of SARS-CoV-2 Spike protein from vaccine obtained
The SARS-CoV-2 Spike protein from a COVID-19 vaccine candidate has been characterised by researchers, supporting the neutralising antibody response it elicits.
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Tuberculosis vaccine shown to protect older mice with type 2 diabetes
A study in older mice with type 2 diabetes revealed a tuberculosis vaccine elicited a strong immune response, making it a promising candidate for the condition.
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Five biomarkers revealed as indicators of COVID-19 patient survival
Five immune response biomarkers have been identified by researchers who say they can be used to classify which COVID-19 patients will survive the disease.
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Largest sequencing study of SARS-CoV-2 presents six separate strains
Researchers have sequenced SARS-CoV-2, revealing at least six strains with little variability, useful information for vaccine developers.
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Coronavirus update: COVID-19 vaccine pre-clinical developments
Drug Target Review rounds up some of the latest news in COVID-19 vaccine candidate R&D.
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Team redesigns COVID-19 Spike protein for more stable vaccines
Researchers have modified the COVID-19 Spike protein for use in vaccines, which produces up to 10 times more protein than that of an earlier synthetic versions.
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Nanoparticle COVID-19 vaccine elicits immune response in pre-clinical studies
The vaccine candidate repRNA-CoV2S elicited both antibody and T cell responses after just two injections in mice and macaques.
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Most antibodies targeting SARS-CoV-2 use specific immunoglobulin subtype
Researchers reveal IgHV3-53 is the most common immunoglobulin mutation used to target the receptor binding domain on the SARS-CoV-2 spike protein.
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Prophylactics for COVID-19 – known and unknown
This article outlines the ideal scientific research that should be conducted to design a prophylactic to combat COVID-19.
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Vaccine adjuvant provides long-lasting protection against HIV in monkeys
A vaccine adjuvant named 3M-052 was able to provide rhesus monkeys with protection against HIV for over a year, a new study reports.
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MMR vaccine could protect against COVID-19 sepsis, paper says
Researchers have suggested that the MMR live attenuated vaccine could be used to provide non-specific protection to patients against sepsis associated with COVID-19.
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Potential for Mycoplasma pneumoniae vaccine through lipoprotein removal, finds study
A new study has shown that effective and safe M. pneumoniae vaccine could be possible by removing certain lipoproteins from the bacteria.
