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Live-imaging technique reveals cellular plug for leaky bio barrier
A microscopy assay has shown the repair mechanism involved in the activation of a protein called Rho, used to plug leaky biological barriers in the body...
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Therapeutics
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Reprogramming stem cells using the measles virus vector
A method has been developed to reprogram stem cells using the measles virus vector, cutting a four-step process to only one stage...
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Reversible antiplatelet therapy fights cancer metastasis and clotting
A novel antiplatelet therapy could help to prevent heart attacks and stroke through preventing the formation of blood clots...
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Development of a gel for liver cell culture on microchips
Hydrogels could be used to build organs on chips to test potential medications, with the aim that they could potentially replace animal studies...
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Diagnostic technique reveals biomarker differentiating bladder cancer from inflammation
A biomarker that can differentiate between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type blood cancer could aid diagnosis...
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Genomic approach to studying widespread malaria
Researchers have suggested that the most widespread human malaria parasite could be studied and possibly treated using genomics...
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Protecting vision after optic nerve trauma using arginase 2
Arginase 2 could be used as a drug target target to protect vision after optic nerve trauma, as removal of this enzyme decreases retinal neuron death...
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Functional transplantable B-cells generated from mice
Stem cells generated from mice have shown to be functional when transplanted, leading to the possibility of future therapies...
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Protection against Mayaro virus using engineered DNA vaccine
An engineered DNA vaccine that induces a robust and specific immune response against the disease, also provides complete protection...
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The role of immune cells in metastasis
Specific immune cells, such as neutrophils, have been found to aid the progression of cancers, promoting metastasis in tumours...
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Key function of specialised cells in peripheral nerve repair
The interaction between macrophages and Schwann cells could be vital in maintaining the repair process, without which could impair nerve function...
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Genetic sequence can predict protein production efficiency
Protein produced in a cell is crucial to maintaining the function of the organism, and this function is important to understand numerous human diseases...
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Mucus could be key to treating colon and airway diseases
The action of proteins that control mucus production could suggest clues to treating colon and airway conditions such as asthma or Crohn's disease...
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The path of metallodrugs in breast cancer cells
The path a metallodrug uses to target and kill cancer cells could be used to design drugs to target triple-negative breast cancer...
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Clusterin linked to both cardiac and metabolic diseases
The protein clusterin has been linked to different cardiometabolic syndrome risks, with researchers asking whether it could be a therapeutic target...
