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CAR T-cell therapy could be harnessed to treat heart disease

11 September 2019 | By Rachael Harper (Drug Target Review)

New study finds immunotherapy reduces cardiac fibrosis and restores heart function in mice after cardiac injury.

news

New biological targets could lead to therapies for drug-resistant cancers

11 September 2019 | By Rachael Harper (Drug Target Review)

A study on how Polycombs regulate cellular identity could lead to alternative treatments for patients with drug-resistant cancer.

article

Five recent Parkinson’s disease drug target discoveries

10 September 2019 | By Victoria Rees (Drug Target Review)

This article highlights five of the latest findings that could be used in the development or design of new therapies to treat Parkinson’s disease.

news

HIV infant model opens new avenues for research

9 September 2019 | By Rachael Harper (Drug Target Review)

An animal model to test HIV infection in infants could lead to biomarkers that predict viral rebound after ART interruption.

news

Tuberculosis mutation discovery could lead to better treatments

6 September 2019 | By Rachael Harper (Drug Target Review)

New gene mutation discovery could lead to more rapid and effective therapies for tuberculosis.

news

ALS pathological mediator identified by researchers

4 September 2019 | By Victoria Rees (Drug Target Review)

A potential target for ALS has been revealed by a study which found the Fos-B gene encouraged axonal branching.

news

Scientists identify promising new target to combat Alzheimer’s disease

4 September 2019 | By Rachael Harper (Drug Target Review)

New research is the first to link maladaptive changes in calcium transport by mitochondria to the progression of Alzheimer's disease.

news

Study presents new ways of developing chronic inflammation treatment

2 September 2019 | By Rachael Harper (Drug Target Review)

Researchers have found a new way to treat the inflammation involved in chronic diseases.

news

Breast cancer ‘sleeper cells’ could be formed after drug treatment

2 September 2019 | By Rachael Harper (Drug Target Review)

Breast cancer medicines may force some cancer cells into 'sleeper mode', allowing them to potentially come back to life after treatment.

news

Gut microbiota in patients with sepsis linked to organ damage

30 August 2019 | By Rachael Harper (Drug Target Review)

The gut microbiota has been linked to organ damage in patients with sepsis suggesting targeting intestinal microbiota may help patients' recovery.

news

Possible treatment discovered for severe dengue disease

28 August 2019 | By Rachael Harper (Drug Target Review)

New findings suggest a possible new treatment strategy for severe dengue disease using the tryptase inhibitor, nafamostat mesylate.

news

Succinate in cystic fibrosis lungs feeds deadly bacteria

23 August 2019 | By Rachael Harper (Drug Target Review)

Targeting a deadly bacteria's use of succinate in the lungs could control infection and improve the health of people with cystic fibrosis.

news

Cyclisation reaction enables screening of macrocyclic compounds libraries

22 August 2019 | By Rachael Harper (Drug Target Review)

Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.

news

New drug target for glioblastoma identified by study

21 August 2019 | By Rachael Harper (Drug Target Review)

A new drug target for treating glioblastoma has been identified from a cellular pathway found to contribute to the spread of glioma stem cells.

news

Genes responsible for gender differences in tumours identified

19 August 2019 | By Rachael Harper (Drug Target Review)

A new study has identified possible regulators that determine differences in cancer tumours between genders.

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