whitepaper Brochure: Biologics workflow solutions brochure 10 November 2021 | By PerkinElmer Biologics solutions from discovery to manufacturing.
news Researchers achieve DNA methylation removal in mouse models 9 November 2021 | By Anna Begley (Drug Target Review) The study showed that DNA “de-methylation” activity can be targeted to anywhere in the DNA and may be a new therapeutic strategy.
news ABI3 gene may be the key to new Alzheimer’s disease therapies 8 November 2021 | By Anna Begley (Drug Target Review) The study found that deleting the ABI3 gene in mice increased plaques and inflammation in the brain, suggesting avenues for new treatments.
news New class of CAR T cells combat previously “untargetable” cancer drivers 4 November 2021 | By Anna Begley (Drug Target Review) The peptide-centric chimeric antigen receptors killed neuroblastoma cells in mice and could potentially expand the pool of immunotherapeutic targets.
news GLP-1 and GIP receptor agonists reduce mouse obesity in pre-clinical study 1 November 2021 | By Anna Begley (Drug Target Review) Treatment with Viking Therapeutics' dual agonists resulted in mean reductions in body weight of up to 27 percent compared to semaglutide-treated animals.
news Scientists target ALS and dementia RNA using novel molecule 28 October 2021 | By Anna Begley (Drug Target Review) The small molecule successfully targeted the C9orf72 gene that causes amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
webinar Capturing biological complexity to empower biomarker discovery 27 October 2021 | By Takara Bio Sign up for this free webinar and discover how refined cell atlases can provide comprehensive roadmaps for health and disease.
news Molecular targets for breast cancer relapse identified in new study 26 October 2021 | By Anna Begley (Drug Target Review) German, Norwegian and British scientists have identified molecular targets for therapies that could prevent breast cancer recurrence.
whitepaper Whitepaper: Phenotypic and functional CAR-T cell characterisation 25 October 2021 | By Sartorius AG This whitepaper overviews phenotypic and functional characterisation of CAR-T cells with advanced flow cytometry and live-cell analysis.
news Measuring microRNAs in blood may indicate dementia risk 14 October 2021 | By Anna Begley (Drug Target Review) Researchers identified three microRNAs whose levels were associated with mental performance in cells, mice and humans.
news Stealth BioTherapeutics reports positive pre-clinical data for ALS candidate 11 October 2021 | By Anna Begley (Drug Target Review) Stealth BioTherapeutic's SBT-272 improved mitochondrial motility in a murine model of amyotrophic lateral sclerosis.
news Pre-clinical trials to test if psychedelic drugs reduce alcohol consumption 8 October 2021 | By Anna Begley (Drug Target Review) Landmark pre-clinical studies to investigate whether psychedelic derivatives can reduce alcohol consumption have been initiated.
news Chemotherapy drug reverses Alzheimer’s symptoms in mice 7 October 2021 | By Anna Begley (Drug Target Review) Axitinib, a common chemotherapy drug, restored memory and cognitive function in mouse models, representing a potential Alzheimer’s treatment.
news Novel “living medicine” could treat antibiotic-resistant infections 6 October 2021 | By Anna Begley (Drug Target Review) Researchers have created the first “living medicine” to treat antibiotic-resistant bacteria growing on the surfaces of medical implants.
whitepaper Application note: Validation of identified through AI 1 October 2021 | By Ncardia Targets for drug discovery can be identified with AI but require validation in vitro. Here’s how this can be done, using hiPSC technology.
