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Circulating cell-free DNA (cfDNA) has been shown to have potential as a noninvasive substrate for the detection and monitoring of tumour cells. As circulating tumour DNA is often present at low frequencies within cfDNA, targeted sequencing is an optimal tool for mutation detection.
Drug target identification has a key role in the drug discovery value chain. A critical step in the development of pharmaceuticals is identifying the direct targets of potential drug candidates as well as distinguishing any secondary or off-target effects...
Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells...
Stevens researchers design and develop a new class of molecules for breast cancer therapy...
Using sugar molecules researchers have developed a new vaccine for hay fever that may reduce treatment times and increase the effectiveness of treatments...
Breakthrough research has uncovered an unexpected mechanism that underlies cardiomyopathy in DMD...
Researchers have identified a potential treatment that will be a foundation for developing drugs for various genetic disorders...
Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...
CMPK2 inhibitors may reduce inflammation, pain and tissue damage in arthritis and gout and in Alzheimer’s may slow loss of cognitive function...
A modified form of botulinum toxin gives long-lasting pain relief in mice without adverse effects...
A protein identified in the signalling pathway for haemoglobin production has been identified as a possible target to treat sickle cell disease (SCD)...
A study has identified microRNA as a possible candidate to be used as a drug target for breast cancer research...
In today’s modern world, data is everywhere. This eBook will guide you through the steps of how to achieve more with accurate data.
New research on how cannabis use alters eating behaviour could lead to treatments for appetite loss in chronic illness...
