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Fullerene compounds could be effective therapy against NSCLC
Researchers have used fullerene compounds to cause NSCLC cell death in cell and animal models, which exhibited low toxicity for healthy cells.
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High-throughput method used to identify cancer drug candidates
A study using high-throughput screening has revealed some promising compounds that could be used in future cancer treatments.
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Lyme arthritis molecule found, providing treatment opportunity
A new study has identified a key molecule involved in Lyme arthritis which presents options for preventative therapies.
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Application note: Tools and protocols for high-content imaging and analysis
Integrating hardware, software and fluorescent labels for optimised HCA assay development.
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Application note: Laser technology for high-content imaging and analysis
Introducing the CellInsight CX7 LZR High-Content Analysis Platform - an updated version of our CellInsight CX7 instrument with advanced laser technology.
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Application note: Tools for 2D and 3D neuronal cell culture
From the B-27 Plus Neuronal Culture System to fluorescent probes for cell analysis. Publication history of B-27 supplements demonstrates that researchers are expanding its use, far beyond the long-term culture of rat hippocampal and cortical neurons.
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Application note: Fuelling discovery with high-content imaging and analysis
HCA platforms automate image capture and data analysis, giving researchers the sample sizes and precise quantitation tools required for research.
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HCA: Phenotypic fingerprint of cellular function
High-content analysis app note: Phenotypic fingerprint of cellular function following gene editing by high-throughput imaging acquisition and analysis.
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HCA Application note: New way of measuring synaptic function
High-content analysis: monitoring neurite morphology and synapse formation in primary neurons for neurotoxicity assessments and drug screening.
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New target for chronic pain relief
Scientists observe drug target that can reduce pain when activated...
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New therapeutic concept controls pathogenic T-cells relevant in MS
Researchers have identified an innovative and promising therapeutic option to treat multiple sclerosis...
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Immunoassay developed to detect small molecules
An immunoassay developed to analyse small molecules has shown 50 times greater accuracy than current systems of analytical techniques...
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Frizzled receptors could be drug targets for treating major diseases
Frizzled receptors, from the GPCR family, could soon be a target to treat numerous diseases such as cancer, fibrosis and CVD...
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ZFP64 protein is key to deadly blood cancer MLL
ZFP64, an inconspicuous MLL fusion protein was found to be neccessary for the production of MLL proteins, and could be targeted to inprove outcomes of MLL...
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Application note: Enabling single-software multiple attribute methodology (MAM) for the assessment of biopharmaceutical product quality attributes
Development and production of biopharmaceuticals is complex. Even minor impurities, or changes in attributes such as glycosylation or charge heterogeneity, can have a profound impact on the safety and efficacy of the final product. Traditionally, multiple analytical techniques have been required to assess the full range of biopharmaceutical product attributes.…
