news
Stem cell therapy with biodegradable scaffold
A biodegradable scaffold used to transplant stem cells and deliver drugs, could help in the treatment of brain diseases...
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Stem Cells
Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.
news
Skeletal stem cells de-differentiate to achieve extensive growth
Researchers in the U.S. have discovered that skeletal stem cells in the jaws of adult mice de-differentiate when tasked with regenerating large portions of bone and tissue.
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GFAP gene mutation creates tangles in brain cells – cause of neurological disease
A recent study in the U.S. has identified how a mutation in the GFAP gene, which encodes for the GFAP protein, causes the tangles in brain cells associated with Alexander disease and may also impact other neurological diseases.
webinar
Integrated fragment-based approach reveals enzymatic inhibitors with potential therapeutic application
25 October 2018 | By NanoTemper Technologies
In this webinar, speakers presented results of integrated fragment-based approaches that have led to the discovery of the first ligands of IDO1 that are able to modulate non-catalytic signalling functions of the enzyme...
news
Helping blood cells to regenerate after radiation therapy
Researchers at MIT have identified a way to stimulate a particular stem cell in order the hasten the regeneration of red blood cells...
news
Cancer stem cells use normal genes in abnormal ways
Researchers have identified that MHC Class I-high, CDK1 high molecules may be at the heart of conditions including melanoma, pancreatic and colon cancers...
news
Umbilical cord stem cells used for early repair of cleft palate
Stem cells harvested from the umbilical cord after birth could lead to a therapy to treat cleft lip and palate without the traditional surgery...
news
New technique generates brain stem cells more efficiently
Scientists in Ohio have developed a more efficient means of creating brain stem cells, specifically oligodendrocyte progenitor cells, or OPCs, which will help facilitate greater understanding of neurological disorders that result from myelin damage.
news
Oxygen sensitive nanoparticles used for 3D printing of complex tissue-like structures
Researchers have implemented oxygen sensitive nanoparticles into a gel material that can be used for 3D printing of complex, biofilm and tissue-like structures...
article
Improved screening of therapeutic candidates using integrated fragment-based approaches
An integrated fragment-based approach, which reveals enzymatic inhibitors with potential therapeutic application, is the subject of this webinar.Taking place on 25 October 2018 at 3:00pm, the webinar is supported by NanoTemper Technologies.
article
Expert view: The development of single‑cell genomics with Smart‑seq
Takara Bio has played a major role in the development of single-cell genomics with the launch of kits such as the automation-ready Smart-seq HT, with a simplified 4-steps protocol. In addition, to meetthe demand for using RNA-seq for degraded clinical samples, we have expanded our offering with a complete sequencing…
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Expert view: Generate high‑content information using flow cytometry
Flow cytometry has become a widely used technology in life science research since its development in the 1970s. It is also essential for many biopharmaceutical and biotechnology companies due to its proficiency in identifying biomarkers, finding new inhibitory antibodies, and assessing the efficiency of new pharmacological protocols.
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Upstream Bioprocessing In-Depth Focus 2018
In this In-Depth Focus: upstream cell culture processes for the production of therapeutic proteins, the evolving role of three-dimensional in-vitro cell culture techniques in drug discovery, and human iPSCs-derived functional cells are revolutionising phenotypic drug discovery and development.
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Expert view: Multiplexed screens in biologics discovery
Biologics are the fastest growing class of therapeutics in the biopharmaceutical industry. A key driver for this growth is success with anti-cancer immunotherapeutics such as checkpoint modulation, adoptive cell therapy and bispecific T-cell engagers. While these approaches use different tactics to attack tumours, they often employ monoclonal antibodies to target…
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Expert view: Large‑scale stem cell expansion and differentiation
Stem cell-based technologies lay the basis for pioneering approaches in drug screening, toxicology testing, and regenerative medicine. The constant supply of high cell numbers in consistent quality needs scalable culture systems and standardised process conditions.
