news MicroRNA in red blood cells causes vascular damage in type 2 diabetes 9 November 2021 | By Anna Begley (Drug Target Review) Researchers discovered that cardiovascular damage was caused by reduced microRNA-210 levels in patient cells and mice with type 2 diabetes.
news Scientists target ALS and dementia RNA using novel molecule 28 October 2021 | By Anna Begley (Drug Target Review) The small molecule successfully targeted the C9orf72 gene that causes amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
news MIT study reveals how lipid imbalance affects cancer growth in mice 21 October 2021 | By Anna Begley (Drug Target Review) In a new study, a calorie-restricted diet significantly reduced tumour growth in mouse models, suggesting new possibilities for cancer therapies.
news Medicenna’s MDNA11 a promising alternative to checkpoint inhibitors 19 October 2021 | By Anna Begley (Drug Target Review) Medicenna's IL-2 super-agonist, MDNA11, successfully induced antitumour cells in animal models, a pre-clinical study has revealed.
news Measuring microRNAs in blood may indicate dementia risk 14 October 2021 | By Anna Begley (Drug Target Review) Researchers identified three microRNAs whose levels were associated with mental performance in cells, mice and humans.
news Scientists uncover answer to colorectal cancer immunotherapy resistance 13 October 2021 | By Anna Begley (Drug Target Review) Boosting dendritic cells prevented immunotherapy resistance in mouse models, suggesting a new approach to colorectal cancer therapies.
news Discovery unveils genetic risk factor shared by Alzheimer’s and COVID-19 12 October 2021 | By Anna Begley (Drug Target Review) Scientists have identified the OAS1 gene as a risk factor for both Alzheimer's disease and COVID-19, suggesting potential drug targets.
news Mesenchymal stem cells could be the key to bone regeneration 11 October 2021 | By Anna Begley (Drug Target Review) Scientists have identified a subpopulation of mesenchymal stem cells with enhanced bone fracture healing and differentiation abilities.
news Small molecule RGX-202 prevents metastasis in colorectal cancer 7 October 2021 | By Anna Begley (Drug Target Review) RGX-202 was found to foil a key pathway that cancer cells rely on for energy in mice, presenting a possible new colorectal cancer therapy.
news Novel “living medicine” could treat antibiotic-resistant infections 6 October 2021 | By Anna Begley (Drug Target Review) Researchers have created the first “living medicine” to treat antibiotic-resistant bacteria growing on the surfaces of medical implants.
news Experimental vaccine a major breakthrough for rheumatoid arthritis 5 October 2021 | By Anna Begley (Drug Target Review) A protein-based vaccine has proven a promising option to prevent rheumatoid arthritis, improving bone quality in animal models.
news Psilera to collaborate with NIDA on pre-clinical psychedelic studies 5 October 2021 | By Anna Begley (Drug Target Review) Psilera will participate in two studies with the National Institute on Drug Abuse to combat addiction using a novel DMT formulation.
news Nobel Prize for medicine awarded to temperature and touch discoveries 4 October 2021 | By Anna Begley (Drug Target Review) David Julius and Ardem Patapoutian have won the 2021 Nobel Prize for Physiology or Medicine, with their work being used to develop treatments for conditions such as chronic pain.
news Gene therapy method could restore visual function after stroke 4 October 2021 | By Anna Begley (Drug Target Review) Scientists have revealed a way to use gene therapy to turn glial brain cells into neurons, restoring vision and potentially restoring motor function.
news Utilising aquaporins could be the key to repairing corneal defects 1 October 2021 | By Anna Begley (Drug Target Review) New evidence suggests that aquaporin 5 (Aqp5) induction promotes corneal epithelial regeneration, which could lead to possible therapies.
