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Ursolic acid, compound in fruit peels, reverses damage in murine model of MS
Ursolic acid was shown to halt the progression of chronic multiple sclerosis (MS) and reverse the damage already caused in a mouse model of the disease.
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Regenerative Medicine
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Increasing numbers of functional stem cells could improve transplants
Exposing umbilical cord blood to NOV proteins causes an increase in functional haematopoietic stem cells (HSCs) and could provide a more effective transplant option for blood cancer patients.
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Connections between nerves and stem cells may be essential for function
Researchers have demonstrated that stem cells attract neurons with different strengths and that connections between the two may be vital for cancer stem cell function.
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Technique for 2D printing of cells developed by researchers
A study has demonstrated the success of a 2D printing method to create cell arrays that reflect the body's natural environment, allowing researchers to study stem cell differentiation.
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How do stem cells repair damage caused by a heart attack?
Researchers exploring how stem cells can be used discovered that cardiopoietic stem cells could repair in tissue in mouse models of heart attacks.
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Exploring future spinal cord injury therapies
Drug Target Review explores five of the latest research developments in the field of spinal cord injury (SCI) repair.
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Muscle cell atlas developed to aid muscular disease and injury research
Researchers have created a new technical resource atlas which maps the 15 distinct cell types involved in muscle repair for disease and therapy research.
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Novel cell reprogramming cocktail could advance regenerative medicine
Scientists have showed that a three inhibitors (3i) cocktail could reprogramme fibroblasts to a naïve embryonic stem cell-like state and remove disease-associated epigenetic changes.
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TEX264 protein could be targeted to help protect DNA from damage
Scientists have identified that the TEX264 protein and associated enzymes protect the genome from damage, which could lead to new anti-ageing and neurodegeneration therapies.
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Stem cells that can grow new bone discovered by researchers
A new population of stem cells that can generate bone has been revealed by researchers, which they say could have implications in regenerative medicine.
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New gene therapy for Huntington’s demonstrates success in mice
Researchers have developed a new regenerative gene therapy using neurogenic differentiation, which has shown efficacy treating Huntington's disease in mice.
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Inhaling stem cell secretome could be a more effective pulmonary fibrosis treatment
Rodent models of pulmonary fibrosis have been used to show that lung spheroid cell secretome therapy is as effective as stem cell secretome treatment.
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Toll-like receptor could be targeted to treat age-related macular degeneration
Scientists have implicated toll-like receptor 2 (TLR2) in age-related macular degeneration and shown that knocking it out can improve symptoms in animal models.
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B cells may travel to remote areas of the brain to improve stroke recovery
Research has found that after stroke in mice, B cells migrate to far regions of the brain that control motor functions, indicating their role in recovery.
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3D printing ‘bio-ink’ developed for regenerative medicine
Using modified hyaluronic acid and polyethylene glycol, researchers have created a bio-ink for 3D printing, which could be used as a scaffold to grow human tissues.
