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Regenerative Medicine

Article: Common CRISPR pitfalls and how to avoid them

9 September 2020 | By Horizon Discovery

This article explains how to plan a gene-editing experiment. How to choose your biological system and what reagents to get for your experimental aim.

Human iPS cells modified with Edit-R™ CRISPR-Cas9 reagents

whitepaper

Application note: Human iPS cells modified with Edit-R™ CRISPR-Cas9 reagents

8 September 2020 | By Horizon Discovery

Modify the genome and modulate expression of genes within human iPS cells with Dharmacon™ Edit-R CRISPR reagents.

Gastric wound - need for bioprinting to treat wound

news

Potential in situ and in vivo bioprinting method developed by researchers

14 August 2020 | By Victoria Rees (Drug Target Review)

Researchers have developed a way for a microrobot to bioprint new cells directly onto gastric wounds inside the body, which they tested in cells.

Stem cells differentiated into heart cells

news

3D printing technique differentiates stem cells into heart cells

12 August 2020 | By Victoria Rees (Drug Target Review)

A new study has shown that 3D printing can be used to control stem cell differentiation into embryoid bodies that replicate heart cells.

opticians image of the retina with a large area of macular degeneration

news

Developing a nanoparticle-delivered gene therapy for blinding eye disease

8 July 2020 | By Hannah Balfour (Drug Target Review)

Ophthalmology and engineering combine in a novel nanoparticle-delivered gene therapy approach to treating wet age-related macular degeneration.

article

The hope of rejuvenation: using plasma to reverse ageing in mice

8 July 2020 | By Victoria Rees (Drug Target Review)

Researchers have found that a plasma exchange process can act as a molecular reset button for old blood, improving the health of ageing mice.

webinar

Drug repurposing approaches to fast track development of new therapies for COVID-19

26 June 2020 | By Tecan

This webinar described the recent efforts to identify small molecule therapeutics for the treatment of SARS-CoV-2 infection and COVID-19 disease.

video

Video: ESHG 2019 conference discussion panel: automated sample preparation

10 June 2020 | By Thermo Fisher Scientfic

A result is only as good as the sample preparation that preceded it.

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

article

Application of organoid technology for retinal disease modelling and drug discovery

4 June 2020 | By Valeria Chichagova (Newcastle University and Newcells Biotech)

The loss of retinal light-sensing photoreceptor cells is a leading cause of blindness and the number of individuals affected by retinal degenerative diseases is increasing with an ageing population. Currently, there are no treatments for these diseases and progress in finding new treatments is slow. This article explores the potential…

article

Using big data approaches to develop cell therapies

4 June 2020 | By Dr Owen Rackham (Duke-NUS Medical School)

An area where stem cell biology and medicine are combining effectively is the establishment of new cell therapies. However, current therapies are limited to a narrow set of cell types that can be isolated or created and expanded in vitro. Dr Owen Rackham discusses how utilising computational approaches will further…

whitepaper

Guide: Five ways biophysical tools help brain studies

3 June 2020 | By NanoTemper Technologies

Learn why researchers turned to biophysical methods to expose the molecular mechanisms of neurodegenerative diseases.

Skull with faded blue outline with a pink brain inside with large red spot

news

Transplanted reprogrammed skin cells repair stroke-damaged rat brains

9 April 2020 | By Hannah Balfour (Drug Target Review)

Skin cells reprogrammed into nerves and transplanted into the stroke-damaged rat brains formed functional connections that restored mobility and touch sensation.

video

Video: Increased reproducibility with KingFisher™ instruments

8 April 2020 | By Thermo Fisher Scientific

ESHG 2019 Conference Presentation: Using KingFisher™ to increase reproducibility in new applications using challenging samples.

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Regenerative Medicine