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Proteomics

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CXCR7 receptor reveals potential therapeutic target to reduce brain inflammation

6 November 2017 | By Dr Zara Kassam (Drug Target Review)

CXCR7 receptor identified as a potential therapeutic target for controlling multiple sclerosis, Parkinson's and AIDS...

news

Blood test developed to diagnose ovarian cancer

1 November 2017 | By Dr Zara Kassam (Drug Target Review)

Non-invasive diagnostic tool measures circulating microRNAs to predict ovarian cancer with specificity...

news

FT4 hormone levels associated with coronary artery disease and death

31 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have indicated that high levels of a thyroid hormone FT4, are associated with coronary artery disease...

news

Modulating FAP may impede pancreatic cancer

30 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers offer a promising target for future therapies that could potentially root out well-hidden metastatic cancer lesions...

news

gp120 protein shows promise in HIV vaccine design

30 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a vaccine candidate that spurs animals to produce antibodies against protective sugars of multiple HIV strains...

news

Mature B lymphocytes accelerate the healing of acute and chronic wounds

27 October 2017 | By Dr Zara Kassam (Drug Target Review)

Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...

news

APC protein affects immunity by preventing pre-cancerous inflammation

25 October 2017 | By Dr Zara Kassam (Drug Target Review)

Mutations in the APC gene, harm the immune system, leaving it unable to tackle inflammation thereby favouring the development of cancer...

news

yTRAP used to quantitatively measure and manipulate protein aggregation

23 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have built a synthetic genetic tool yTRAP to quantitatively sense, measure and manipulate protein aggregation in live cells...

news

dCA accelerates HIV-1 suppression in chronically infected cells

18 October 2017 | By Dr Zara Kassam (Drug Target Review)

Didehydro-Cortistatin A effectively suppresses production of the HIV virus in chronically infected cells and prevents viral rebound...

news

A3G protein fights HIV as monomer and dimer

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

A human protein A3G inhibits HIV-1 by acting as a roadblock for further replication of the virus...

news

FRET imaging used to establish a beachhead at the NMDA receptor gate

10 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers use light-sensitive molecules to track proteins critical to cell signalling...

news

TREM2 gene mutation poses both risk and benefits in Alzheimer’s disease

9 October 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have identified that a mutation in the gene TREM2, can substantially raise a person’s risk of Alzheimer’s disease...

news

Link between bacterial imbalances and breast cancer identified

9 October 2017 | By Dr Zara Kassam (Drug Target Review)

Bacterial composition of breast tissue could offer a new perspective in the battle against breast cancer...

news

E6/Myc binding provides potential treatment strategy for HPV

2 October 2017 | By Dr Zara Kassam (Drug Target Review)

A study that teases apart the biological mechanisms by which HPV cause cancer, has found a strategy that may provide targeted treatment...

news

NRF2 pathway provides new approach to cancer drug discovery

2 October 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have developed a promising new strategy for the discovery of novel anti-cancer therapies for non-small-cell lung cancers...

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