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Frizzled receptors could be drug targets for treating major diseases
Frizzled receptors, from the GPCR family, could soon be a target to treat numerous diseases such as cancer, fibrosis and CVD...
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Protein Expression
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Inhibiting USP13 destroys toxic clumps seen in Parkinson’s disease
A team of neurologists have found that one reason Lewy bodies develop is that a molecule, USP13, has removed all the "tags" placed on alpha-synuclein that mark the protein for destruction...
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Swarm of exosomes protect against inhaled bacteria
A swarm of billions of exosomes armed with proteins has been shown to assist in the fight against bacteria inhaled through the nose...
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GFAP gene mutation creates tangles in brain cells – cause of neurological disease
A recent study in the U.S. has identified how a mutation in the GFAP gene, which encodes for the GFAP protein, causes the tangles in brain cells associated with Alexander disease and may also impact other neurological diseases.
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Protein sequencing method could transform biological research
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
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Atg2 tethers pre-autophagosomal membranes to endoplasmic reticulum
Researchers at Tokyo University have investigated the role of the Atg2 protein in the process of autophagy to aid drug discovery into neurodegeneration...
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Single molecule fluorosequencing to transform biological research
Single molecule fluorosequencing could revolutionise the way researchers analyse disease, with the method enabling the investigation of single cells...
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Promising new vaccine developed for vivax malaria
A study indicates the possibility of using tiny vesicles derived from human immature red blood cell as a vaccine platform...
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The molecular link between ageing and neurodegeneration
Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...
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Cocaine relapse is reversed with BDNF microinjections in the brain
Researchers have discovered that a very common protein in the brain has an additional significant role in addiction relapse...
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Research into cellular signalling mechanisms may lead to new treatments
Wnt moves to specific areas of the cell membrane, interacting with a receptor known as Ror2, and inducing the formation of a cytoneme...
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Key role of PI3Ky in Chagas disease described
The expression of PI3Ky increases during infection by T.cruzi, providing an essential response controlling the parasite and avoiding inflammation...
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How does Parkinson’s disease develop?
Study raises doubts on a previous theory of Parkinson’s disease...
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SMCHD1 protein found essential to X chromosome inactivation
The structural protein is required for the chromosome to adopt a conformation that suppresses gene expression...
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Blood test rapidly detects signs of pancreatic cancer
A new diagnostic test developed by researchers at UC San Diego shows promise for detecting pancreatic cancer earlier...
