Precision medicine

Study provides insight into blood signatures of inflammation

9 May 2018 | By Drug Target Review

A new study has identified a pattern of inflammation associated with cardio-metabolic risks...

ALS researchers begin recreating human spinal cords on a chip

30 April 2018 | By Dr Zara Kassam (Drug Target Review)

NIH-funded study closes in on personalised drug testing for neurological disorders...

Transforming translational research: CANscript^TM – A better predictive model for oncology

27 April 2018 | By Mitra Biotech

In this webinar, speaker Mark Paris, PhD discussed a recent study evaluating a cohort of HNSCC patient tumours treated with anti-PD1 using CANscript TM;. He also be reviewed the results of this study as a means of investigating predictors of clinical response and identifying mechanisms of resistance.

Biomarker endpoints for Parkinson’s disease

26 April 2018 | By Charles River Laboratories

This webinar provides a comprehensive review of the validation data from established and novel animal models of Parkinson’s disease.

Rare brain disease in children: Major breakthroughs in Rasmussen’s encephalitis

11 April 2018 | By Dr Zara Kassam (Drug Target Review)

Chronic focal encephalitis is a rare and devastating inflammatory brain disease, researchers have proven that the disease attacks patients using their own immune system...

How the study of lipidomics is benefiting from recent advances in mass spectrometry

10 April 2018 | By Cristina Legido-Quigley (Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen)

There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.

An advance for precision medicine

10 April 2018 | By Drug Target Review

Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...

Mitra Biotech

3-D tissue model of developing heart could help drug safety testing

20 March 2018 | By Drug Target Review

Researchers have combined biomaterials-based cell patterning and stem cell technology to make a 3D tissue model that could mimic early stage human heart development...

Under the microscope: Choosing the best microplate reader

19 March 2018 | By Mark Wigglesworth (Director High-Throughput Screening - AstraZeneca)

Efficient microplate readers play an important role in effective hit molecule discovery. Mark Wigglesworth, of AstraZeneca, explains what he looks for in this technology.

Pancreatic stem cells have potential to regenerate beta cells

1 March 2018 | By Dr Zara Kassam (Drug Target Review)

Findings pave way for regenerative cell therapies in type 1 diabetes patients...

Metabolomics heralded as encouraging tool for personalised treatment of cancer

16 February 2018 | By Drug Target Review

Researchers in Spain provide specific examples of metabolomics applications in the field of clinical pharmacology and precision medicine, focusing on the therapeutic management of cancer.

PSMA PET/CT imaging provides precision radiation therapy for prostate cancer

2 February 2018 | By Dr Zara Kassam (Drug Target Review)

A nuclear medicine scan may locate prostate cancer recurrence after radical prostatectomy early after disease recurrence and could help guide salvage radiotherapy...

Raman imaging technique shows Alzheimer’s disease progress in the brain

24 January 2018 | By Drug Target Review

Using Raman optical technology, scientists can now produce images of brain tissue that is affected by Alzheimer’s disease...

Immune cells dictate tumour progression

15 January 2018 | By Dr Zara Kassam (Drug Target Review)

Analysing individuals' genotypes and immunotypes could yield customised treatments for prostate cancer...