Personalised Medicine

Study provides insight into blood signatures of inflammation

9 May 2018 | By Drug Target Review

A new study has identified a pattern of inflammation associated with cardio-metabolic risks...

Whitepaper: Smart cell monitoring

3 May 2018 | By Del Trezise, Essen BioScience

This whitepaper outlines how advances in real-time live-cell monitoring and analysis methods are addressing these changing needs.

Transforming translational research: CANscript^TM – A better predictive model for oncology

27 April 2018 | By Mitra Biotech

In this webinar, speaker Mark Paris, PhD discussed a recent study evaluating a cohort of HNSCC patient tumours treated with anti-PD1 using CANscript TM;. He also be reviewed the results of this study as a means of investigating predictors of clinical response and identifying mechanisms of resistance.

Automated assessment of Liver and Cardiac toxicities in lead optimisation, using biochemical and human iPS cell assays

27 April 2018 | By TECAN

ABOUT THIS WEBINAR: In this two-part webinar, both automation of P450 (CYP) assays and the automatisation of cellular differentiation processes and compound testing using human induced pluripotent stem cells based assays was covered.   Metabolism of drugs is a key factor in compound toxicity, and automated assays which monitor inhibition or…

The European Life Sciences Community meets at BASEL LIFE

13 April 2018 | By BASEL Life Science

Leading experts of the European Life Sciences Community are engaging under the name BASEL LIFE to establish a bridge between science and business.

Rare brain disease in children: Major breakthroughs in Rasmussen’s encephalitis

11 April 2018 | By Dr Zara Kassam (Drug Target Review)

Chronic focal encephalitis is a rare and devastating inflammatory brain disease, researchers have proven that the disease attacks patients using their own immune system...

How the study of lipidomics is benefiting from recent advances in mass spectrometry

10 April 2018 | By Cristina Legido-Quigley (Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen)

There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.

Mitra Biotech

Lancet tool enables accurate identification of rare mutations in cancer cells

26 March 2018 | By Dr Zara Kassam (Drug Target Review)

A new computational method allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity...

Under the microscope: Choosing the best microplate reader

19 March 2018 | By Mark Wigglesworth (Director High-Throughput Screening - AstraZeneca)

Efficient microplate readers play an important role in effective hit molecule discovery. Mark Wigglesworth, of AstraZeneca, explains what he looks for in this technology.

Extracellular vesicles could be personalised drug delivery vehicles

15 March 2018 | By Drug Target Review

Researchers developed an approach and platform to create large amounts of fillable and targeted nanovesicles to deliver drugs to tumours in mice...

Pro72Arg gene variant increases tumour cell metabolism

1 March 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have found a mechanism through which mutant p53 enhances metastasis by controlling tumour metabolism...

Charles River Laboratories announces new tumour model compendium

28 February 2018 | By Charles River Laboratories

The Compendium provides scientists an online resource to help design efficient in vitro and in vivo oncology research studies.

Neural stem cell treatment may offer relief for MS

27 February 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have shown that skin cells re-programmed into brain stem cells, transplanted into the central nervous system, help reduce inflammation and may be able to help repair damage caused by MS...

Gene manipulation holds the key to personalised medicine

5 February 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers propose a novel approach to manipulate genes that may hold the key to the future of personalised medicine...