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Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
This webinar, held on 25 October 2018, presented the results from integrated fragment-based approaches for Indoleamine 2,3 dioxygenase 1 (IDO1), an enzyme widely recognised as a drug target for the development of immunotherapeutic small molecules in oncology, unveiling the first ligands able to modulate non-catalytic signalling.
Series of molecules may provide more reliable relief with fewer side effects...
Discovery based on analysis of tissue and saliva samples from oral cancer patients shows a correlation between a signature comprising three peptides and the presence of lymph node metastasis...
In lab and mouse experiments researchers have developed a method to leverage B cells to manufacture and secrete tumour-suppressing microRNAs...
Researchers have genetically engineered immune cells to recognise and fight Hodgkin and non-Hodgkin lymphoma cells...
Nanoscientists have identified genes that link to dementia, in the hope that future therapies could target these genes for positive results in patients...
Manchester University researchers have developed a high-throughput platform to analyse and study a family of enzymes that are linked to cancer...
Circulating cell-free DNA (cfDNA) has been shown to have potential as a noninvasive substrate for the detection and monitoring of tumour cells. As circulating tumour DNA is often present at low frequencies within cfDNA, targeted sequencing is an optimal tool for mutation detection.
A recently discovered enzyme could lead to the development of a treatment where cancer cells are starved of 'food' provided by this protein...
Laura Kilpatrick, Chloe Peach and Carl White from the University of Nottingham talk about cancer research and how they use our microplate readers PHERAstar and CLARIOstar.
Mouse models used to show how convection enhanced delivery caused glioma cells to invade the rest of the brain could help to prevent this spread in future...
War On Cancer 2018 discussed how cancer treatments have evolved over the last few decades, and looked at the future of cancer therapies...
Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells...
Team of oncology experts expand data in Tumor Model Compendium and present strong portfolio at industry conferences...
RIP1 has been shown to suppress the action of macrophages against the immune system and could be a potential therapeutic target for pancreatic cancer...
