Drug compound could be next-generation treatment for aggressive form of AML
Researchers have developed a series of compounds that work not only on AML with common FLT3 mutation but also drug-resistant AML...
List view / Grid view
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
Researchers have developed a series of compounds that work not only on AML with common FLT3 mutation but also drug-resistant AML...
Preclinical study yields previously unreported, potent and generalisable hits representing potential drug targets for hereditary breast, ovarian cancer...
Researchers have found a way to activate macrophages that have been forced to help cancer grow and spread around the body...
Researchers have identified how they can differentiate between lesions in the airways that are benign and those that could become cancerous...
Identified using a computer algorithm, the NSD2 gene may be responsible for advancing the spread of prostate cancer, and so could be used as a drug target...
Researchers in the US have discovered how a gene involved in regulating hormone receptors, GREB1, may contribute to drug resistance in some prostate cancer patients.
Immunotherapy and targeted treatments, including targeted chemotherapy, continue to show great potential in cancer care. Future steps in their development will involve improving their ability to treat a wider range of cancers and a broader cross-section of the patient population, especially those for whom current treatments have shown limited efficacy...
High level of specific protein in tumours indicates prognosis as well as optimal treatments...
A study has found that the immune system can be harnessed to fight cancer cells in a particularly efficient manner, one also effective in lung cancer...
A mouse study has revealed that triple-negative breast cancer could be tackled by using recombinant Tinagl1 in therapy targeting signalling pathways...
Machine learning could, in future, be the way that clinicians decide on particular courses of treatments for patients affected by cancer...
Proteomics research has become a popular method for characterising functional proteins as well as discovering the innovative targets for oncologic disorders...
A new method for correcting the errors that creep into DNA barcodes has paved the way for more ambitious medical research...
The enzyme protein kinase C delta (PKCδ) found in NSCLC tumors prevents tyrosine kinase inhibitors (TKIs) from forestalling cancer...
Rapid drug response screening for leukaemia stem cells offers clues to relapse and to improving patient-specific therapies...