news UTX gene mutation “robs” individuals of natural cancer protection 10 November 2021 | By Anna Begley (Drug Target Review) The UTX gene mutation was found to lead to an increased cancer risk, presenting a potential drug target for preventative therapies.
news Scientists explore CA2 neuron mitochondria for memory loss targets 10 November 2021 | By Anna Begley (Drug Target Review) The team will receive $2 million over five years to investigate the CA2 brain region for the development of neurological therapies.
news Novel intestine chip enables effective in vitro study of COVID-19 therapies 10 November 2021 | By Anna Begley (Drug Target Review) The intestine chip was infected with a coronavirus to test a variety of drugs, presenting a new method to investigate COVID-19 treatments.
news Fruit flies could unveil new genetic targets for obesity treatment 5 November 2021 | By Anna Begley (Drug Target Review) Researchers used obese fruit flies to analyse how gene activities affect triacylglyceride levels, unveiling novel drug targets for obesity.
news Pathway and enzyme responsible for CKD thrombosis identified 2 November 2021 | By Anna Begley (Drug Target Review) Scientists have discovered a novel pathway and enzyme that causes thrombosis in chronic kidney disease (CKD) patients, indicating a new drug target.
news Raman spectroscopy used to determine immunotherapy effectiveness 28 October 2021 | By Anna Begley (Drug Target Review) Researchers used Raman spectroscopy to monitor immunotherapy response in mice, potentially improving cancer treatments in the future.
news Experimental mouse model reveals potential progeria treatment strategy 27 October 2021 | By Anna Begley (Drug Target Review) Scientists have found that Hutchinson-Gilford Progeria Syndrome (HGPS) can be prevented with treatments targeting the cardiovascular system using a novel mouse model.
news Molecular targets for breast cancer relapse identified in new study 26 October 2021 | By Anna Begley (Drug Target Review) German, Norwegian and British scientists have identified molecular targets for therapies that could prevent breast cancer recurrence.
news New antibiotic a possible alternative to treat Lyme disease 20 October 2021 | By Anna Begley (Drug Target Review) The antimicrobial hygromycin A was shown to clear Lyme disease in mice, representing a promising therapeutic against the disease.
news Senescent cell treatment could combat age-related diseases 20 October 2021 | By Anna Begley (Drug Target Review) Scientists have developed a novel technique for the targeted clearance of senescent cells to improve treatments for ageing and other conditions.
news Antibiotic-free hydrogel fights against drug-resistant bacteria 19 October 2021 | By Anna Begley (Drug Target Review) New dendritic hydrogels were tested against several infectious bacteria and could be used as an an antibiotic-free treatment in the future.
news New single-cell and metagenomic technique can characterise microbes 14 October 2021 | By Anna Begley (Drug Target Review) The metagenomic method, termed SMAGLinker, could improve the accuracy and resolution of microbial characterisation to improve medicine design.
news Mission Therapeutics receives $500k grant for Parkinson’s research 14 October 2021 | By Anna Begley (Drug Target Review) Mission Therapeutics was granted $500,000 from the The Michael J Fox Foundation for Parkinson’s Research for DUB inhibitor testing.
news Neurolysin shown to be potential drug target for ischemic stroke 13 October 2021 | By Anna Begley (Drug Target Review) Researchers are identifying molecules that interact with neurolysin, a peptidase that helps protect the brain against stroke.
news Scientists uncover answer to colorectal cancer immunotherapy resistance 13 October 2021 | By Anna Begley (Drug Target Review) Boosting dendritic cells prevented immunotherapy resistance in mouse models, suggesting a new approach to colorectal cancer therapies.