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microRNA

anatomical drawing of the male reproductive/urinary system with the prostate highlighted in red

news

Novel prostate cancer resistance mechanism could be a promising target

6 January 2021 | By Hannah Balfour (Drug Target Review)

By inhibiting the activity of microRNA-194 (miR-194), scientists prevented prostate cancer cells from developing treatment resistance in vitro.

SARS-CoV-2 particles in grey and red - SARS-CoV-2 is the virus that causes COVID-19

news

Single interaction could explain the disparity in COVID-19 effects

17 December 2020 | By Hannah Balfour (Drug Target Review)

According to researchers, an interaction between host microRNA and SARS-CoV-2 could be responsible for the range of disease severities.

news

Drug target for spinocerebellar ataxia type 1 identified by researchers

10 August 2020 | By Victoria Rees (Drug Target Review)

A team has found that a mutation in the ATAXIN-1 gene causes spinocerebellar ataxia type 1 (SCA1), presenting a drug target for the condition.

article

Coronavirus update: COVID-19 vaccine pre-clinical developments

5 August 2020 | By Victoria Rees (Drug Target Review)

Drug Target Review rounds up some of the latest news in COVID-19 vaccine candidate R&D.

news

Study reveals microRNA as promising hair regrowth drug target

28 July 2020 | By Victoria Rees (Drug Target Review)

Researchers have revealed that the microRNA miR-218-5p promoted hair growth in mice, so is a promising drug target for hair loss.

news

Novel biomaterial could be used to accelerate bone regeneration

15 June 2020 | By Victoria Rees (Drug Target Review)

In lab conditions, a new biomaterial was able to accelerate bone regeneration by boosting an immune response that encourages repair.

news

Novel pathway to target colorectal cancer identified

29 November 2019 | By Rachael Harper (Drug Target Review)

Researchers have found that PGE2, a signalling molecule involved in inflammation, promotes colorectal cancer progression through a microRNA and targeting that microRNA could have therapeutic potential.

news

microRNA could lead to new methods to treat multiple sclerosis

27 November 2019 | By Rachael Harper (Drug Target Review)

In a pre-clinical model of multiple sclerosis, orally treating susceptible mice with a microRNA from the diseased gut has prevented the disease.

news

CNS tumour aggressiveness reduced with new molecule

8 November 2019 | By Rachael Harper (Drug Target Review)

A microRNA inhibitor has been identified which reduced the sizes of aggressive CNS tumours and improved survival in mice.

news

New mechanism of controlling fat production revealed

18 September 2019 | By Rachael Harper (Drug Target Review)

A new study has shown a new mechanism of controlling fat production in the body which could lead to new therapies to treat obesity.

news

New research advances the possibility of regenerating tissue after a heart attack

23 April 2019 | By Drug Target Review

This research advances the possibility of reviving the heart's regenerative capacities using microRNAs.

news

Engineered dl355 virus has the potential to be an effective anticancer treatment

30 January 2019 | By Dr Zara Kassam (Drug Target Review)

An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers...

news

Chromatin study unearths link between DNA-protein binding and cancer

31 October 2018 | By Drug Target Review

A team of scientists led by Stanford University School of Medicine has identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers to predict cancer pathways and long-term patient outcomes.

news

miR-31 may help target treatments for Crohn’s patients

16 October 2018 | By Drug Target Review

Researchers have pinpointed a single molecule - microRNA-31 (miR-31) - the levels of which predict whether a patient has subtype 1 or subtype 2 of Crohn's disease...

news

Small molecule factors found to influence age-related bone deterioration

18 September 2018 | By Drug Target Review

Scientists in the U.S. have reported findings about the mechanisms that contribute to the experience of weaker bones with age.

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