news
Intestinal bacteria found to produce SARS-CoV-2-inhibiting compounds
Researchers have screened bacteria in the gut, finding that Bifidobacteria have inhibitory activity against SARS-CoV-2.
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Microbiology
news
Mass spec method developed to identify drugs to fight resistant bacteria
Researchers have developed a native state mass spectrometry technique to identify inhibitors of the bacterial protein metallo-beta-lactamase.
news
Researchers use exosomes to develop potential salmonella vaccine
Exosomes containing salmonella antigens were administered to the mice, enabling the models to develop antibodies against the bacteria.
news
AI platform developed to reveal how bacteria infect intestines
A new artificial intelligence (AI) method has been created to uncover which proteins enable bacteria to infect human intestines.
news
Drug development platform could provide targeted antimicrobials
Researchers have developed a platform named FAST to produce antibiotics that specifically target just the bacteria of interest.
news
Researchers modifiy E. coli to produce chondroitin sulphate
A team has created a biosynthetic pathway for E. coli that allows the bacteria to produce a common arthritis drug.
article
High-throughput laboratory evolution reveals how bacteria gain drug resistance
This article introduces insights into combatting multidrug resistance via high-throughput laboratory evolution, pointing to the mechanisms of underlying evolved drug resistance.
news
RNA sequencing reveals insight into tuberculosis infection
Using single-cell RNA sequencing, researchers have shown that interferon response is correlated with tuberculosis progression.
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ES17 phages can destroy bacteria before gut infection in mice
A study has shown that the ES17 phage binds to heparan sulphate and can target and eliminate ExPEC bacteria in animal models.
news
CBD shown to kill Gram-negative bacteria in pre-clinical studies
Researchers have shown that CBD can kill Gram-negative bacteria, which could lead to the first new class of antibiotics for resistant bacteria in 60 years.
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Scientists identify nutrient that helps prevent bacterial infection
Scientists have identified a potential alternative to antibiotics, a nutrient named taurine that helps the microbiome kill invading bacteria.
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Role of retrons in bacteria revealed, with potential for use in gene editing
The role that retrons in bacteria has been discovered by researchers, who found they protect colonies when infected by viruses.
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Adding to the arsenal: targeting human proteins for controlling M. tuberculosis growth
The National Institute of Health envisions a plan for managing tuberculosis in the 21st century. Included in this proposal is targeting host proteins as an add-on therapy to antibiotics. Infectious disease biologists are focusing on this strategy and it is a topic of active research. Recently, a multinational research team…
news
Imaging and machine learning system created to discover tuberculosis drugs
Researchers have developed MorphEUS, a technology to identify new drugs that combat M. tuberculosis by revealing how compounds destroy the bacteria.
webinar
Drug repurposing approaches to fast track development of new therapies for COVID-19
26 June 2020 | By Tecan
This webinar described the recent efforts to identify small molecule therapeutics for the treatment of SARS-CoV-2 infection and COVID-19 disease.
