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Medicinal chemistry

Human iPSC-derived cardiomyocytes for cardiac proarrhythmic risk assessment

27 October 2021 | By Anton Simeonov, Drug Target Review, Victoria Rees (Drug Target Review)

Following Drug Target Review's webinar supported by Eurofins, speaker Dr Verena Albert answers the questions posed by the audience during the live event.

Label-free compound profiling automation

article

Sample preparation automation in label-free compound profiling

31 August 2021 | By Drug Target Review

Following the latest Drug Target Review webinar, supported by Analytik Jena, we put the audience’s questions to the speakers to understand how hardware, software and labware challenges can be successfully overcome.

news

Bioactivity information of one million molecules compiled

1 July 2021 | By Victoria Rees (Drug Target Review)

Using deep machine learning, researchers have completed the activity profiles, from chemistry to clinical level, for one million molecules.

article

Millennia in the making: unlocking the medicinal value of CBD

20 May 2021 | By Dr Sotirios Karathanasis (Enveda Biosciences)

Dr Sotirios Karathanasis discusses the history of cannabis as a treatment and delves into the process of turning plant-based medicines into clinically proven drugs.

news

Automated method to produce synthetic DNA created

13 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed a technique to synthetically produce DNA oligonucleotides that avoids the degradation of phosphoramidites.

news

Novel PF74-like small molecules developed to target HIV capsid protein

9 April 2021 | By Victoria Rees (Drug Target Review)

Scientists have developed PF74-like small molecules able to target the HIV-1 capsid protein, identifying four potent compounds.

news

Team modifies therapeutic molecule to improve stroke treatment

19 February 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown that adding a polymer to glutamate-oxaloacetate transaminase means the molecule can treat stroke for up to six days in rats.

news

Kenpaullone protects from cisplatin-induced hearing loss

7 March 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 protects mice and rats from noise- or drug-induced hearing loss...

news

BenevolentAI hires new head of Cheminformatics from The Institute of Cancer Research

20 July 2017 | By Dr Zara Kassam (Drug Target Review)

BenevolentAI announced today it has hired Dr Nathan Brown, as its new Head of Cheminformatics following the promotion of Mark Davies...

news

A*STAR and MSD team up to advance peptide therapeutics

19 July 2016 | By Niamh Louise Marriott

A*STAR and MSD have formed a two year collaboration aimed at improving cellular delivery of macrocyclic peptides...

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Medicinal chemistry