news
Researchers develop synthetic bioluminescence to view body’s cells externally
Researchers in Japan have ramped up nature’s wonder that is bioluminescence to enable deep tissue cells to be seen from outside the body.
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Effective drug transfer tests look promising for placenta-on-a-chip technology
Researchers in America have demonstrated the feasibility of their ‘placenta-on-a-chip’ platform in studying how drugs are transported across the human placental barrier.
webinar
Streamlining drug discovery assays for cancer and cardiovascular disease
1 February 2018 | By PerkinElmer
This webinar discussed a screening assay that recapitulates the activation of ER stress sensor IRE1 and an assay to quantify cell migration phenotypes, as applied to cardiovascular target validation and drug discovery.
news
New radiotracer differentiates bacterial infection from inflammation in lungs
Researchers at the University of Louisville, Kentucky, have demonstrated that a new radiotracer, 2-18F-fluorodeoxysorbitol (18F-FDS), can identify and track bacterial infection in lungs better than current imaging methods and is able to differentiate bacterial infection from inflammation.
article
Identification of hits and leads for human African trypanosomiasis
Neglected tropical diseases (NTD) affect more than one billion people and new targets and drugs are needed to tackle these infections. The multi-disciplinary NMTrypI consortium has identified a number of different compound classes which could be effective against these diseases. This article reviews some of these compounds...
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Charles River adds ERS License to CRISPR/Cas9 service offering
Charles River Laboratories International, Inc. announced the expansion of its CRISPR/Cas9 service offering with the addition of a license from ERS Genomics Limited.
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Charles River Laboratories presents newly expanded capabilities at Neuroscience 2017
Charles River Laboratories International, Inc. announced that its team of neuroscience drug discovery experts is presenting 27 scientific posters, both independently and collaboratively with clients, at Neuroscience 2017, the 47th annual meeting of the Society for Neuroscience (SfN).
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Charles River announces expansion of in vitro oncology services
Partnership with InSphero provides additional 3D solutions...
webinar
Integrated drug discovery panel – your questions answered!
28 September 2017 | By Charles River
During this peer panel discussion, team members from Charles River discussed their views and strategies on Drug Discovery...
news
Magnetic cellular ‘Legos’ for the regenerative medicine of the future
By incorporating magnetic nanoparticles in cells researchers have succeeded in creating cellular magnetic "Legos."...
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PerkinElmer launches new IVIS® Lumina™ S5 and Lumina X5 systems for high throughput in vivo imaging
Advanced 2D imaging and analysis help scientists rapidly trace anatomical and molecular aspects of diseases to advance drug discovery...
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Cell culture system could offer cancer breakthrough
A new cell culture system that provides a tool for preclinical cancer drug development and screening has been developed...
news
Novel immunotherapy technology for prostate cancer
Scientists have described a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA...
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Bioprinted veins reveal new drug diffusion details
A scientific collaboration has developed vascularised 3-D bioprinted liver tissue constructs, providing more precise drug toxicity testing...
news
Polyphor achieves first milestone from Wellcome for antibiotic development
Polyphor achieves first milestone from Wellcome Trust for the development of antibiotics against Gram-negative multi drug - resistant pathogens...
