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Study in the U.S. demonstrates successful treatment of advanced melanoma and metastatic cancer using a new bacteria-like agent combined with an immunotherapy drug.
Patients who are unlikely to benefit from a commonly used immunotherapy for bladder cancer could be identified by a simple blood test...
Researchers have developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors...
Researchers have identified a gene that when inhibited, reduced human non-small cell lung cancer tumours from growing...
A gene that's associated with an autoimmune form of hair loss could be exploited to improve cancer immunotherapy...
Quickly and easily quantitate immune checkpoint markers using a fraction of the sample volume required by traditional ELISAs...
Exclusive interview with Grace Macaulay - MedImmune released in the run up to the Immuno-Oncology Conference, taking place on the 26 - 27 September 2018 in London.
Researchers report that in preclinical models they can amplify macrophage immune responses against cancer using a self-assembling supramolecule...
Using data from multiple molecular databases, researchers from the University of Pennsylvania have found nine distinct types of exhausted T cells (‘Tex’), which could have implications for fighting chronic infections, autoimmunity, and cancer.
A CAR-T-based immunotherapy successfully kills tumours and prevents metastatic growth, in final preclinical tests before human trials...
Research led by the University of Birmingham has identified a novel unconventional type of immune cell capable of fighting viral infections.
This article focuses on how the immune system functions, the challenges that it presents to drug development and why there are such concerns around safety that need to be investigated in pre-clinical studies. Moreover, it covers the role of checkpoint inhibitors as an attractive target for cancer immunotherapy.
Scientists in Switzerland have uncovered a potential means of increasing effective treatment of melanomas with immunotherapy, by disrupting the action of macrophages.
Researchers at the Medical University of South Carolina (MUSC) have identified a novel checkpoint of peripheral tolerance, specifically in B cells.
The immune system is now regarded as a powerful weapon in the war against cancer, and in the current era immune cells have become ‘living drugs’. This review article considers some of the key advances in immuno-oncology...
