news
HIC1 protein may protect against intestinal disease
Scientists find molecular link between Vitamin A derivative and mouse intestinal health...
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Immunology
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Local environment plays key role in breast cancer progression
While studying the complex correlation between tissue stiffness and breast cancer development, researchers found that cancer cells tend to become more aggressive when the surrounding tissue stiffens...
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Lipid asymmetry plays key role in activating immune cells
Researchers have shown that by preventing loss of membrane asymmetry it's possible to control the immune response...
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BX795 molecule clears HSV-1 infection in human corneal cells
Researchers at the have identified a small drug molecule that can clear the herpes simplex virus-1 infection, making it a promising potential option for patients who have developed resistance...
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Immune system found to protect against MRSA infections
Researchers have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus...
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Searching for targeted treatments for inflammatory diseases
Scientists have identified identified key regulators that are essential for controlling the inflammatory response in Crohn’s disease and multiple sclerosis.
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Study suggests PD-1 inhibitors against aggressive pediatric brain cancer subtype
A study has laid the groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer, namely supratentorial pediatric ependymoma.
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Immune cells dictate tumour progression
Analysing individuals' genotypes and immunotypes could yield customised treatments for prostate cancer...
whitepaper
Application note: Development and utilisation of bromodomain and extra terminal domain (BET) assays using AlphaLISA technology
In this application note, PerkinElmer demonstrates the ease and utility of using AlphaLISA®, a homogeneous assay format, to screen for small molecular inhibitors of BET bromodomains.
webinar
Using open science to develop Pediatric Cancer Drugs
2 January 2018 | By Charles River Laboratories
The webinar speakers highlight the collaboration between patient groups, charities, and academia led to the development of inhibitors targeting gliomas.
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Researchers create anti-inflammatory antibodies to treat autoimmune disease
Massachusetts General Hospital (MGH) investigators use enzyme treatment to convert autoantibodies into anti-inflammatory antibodies in animal models of two autoimmune diseases.
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Stem cell-derived intestine model mimics innate immune responses
A stem cell-derived in vitro model displays key small intestine characteristics including innate immune responses.
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Mature B lymphocytes accelerate the healing of acute and chronic wounds
Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...
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DNA-based Zika vaccine found effective at inducing immune response
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
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Cytokine molecules unearth development of progressive MS
Scientists have uncovered two closely related cytokines molecules involved in cell communication that explain why some people develop progressive MS...
