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Free radicals from immune cells cause salt-sensitive hypertension
A new study has found that in salt-sensitive hypertension, immune cells gather and release free radicals, damaging the kidneys.
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Immunology
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Molecular ‘switch’ could help treat or reverse age-related diseases
A molecular 'switch' that controls the immune machinery responsible for chronic inflammation has been identified which could help treat or even reverse the development of age-related conditions like Alzheimer's, Parkinson's, cancer and diabetes.
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Immune system regulator shifts immune cell balance
Researchers have provided new insight into the role of cyclic AMP (cAMP) in regulating the immune response which may lead to new ways of treating diseases.
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Blocking IL-17 could provide new multiple sclerosis treatment strategy
Researchers have revealed that inhibiting IL-17 could prevent the effects of autoimmune diseases, including multiple sclerosis.
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Molecule of blood found to be effective against lupus
Scientists have found that a molecule present in our blood, called C4BP (β-), could be used in a therapeutic capacity for lupus as well as potentially other autoimmune disorders.
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Study identifies gene responsible for T follicular helper cell development
A loss-of-function mutation in the Prkd2 gene has been revealed as a driver of T follicular helper cell development which could be useful for vaccine design.
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Researchers discover how gut infections may produce chronic symptoms
A new study into why neurons in the gut die and how the immune system protects them could lead to better treatments for IBS that work by boosting polyamine production.
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Process that immune cells use to detect infections and cancers discovered
Researchers have discovered how gamma-delta T cells become activated which could lead to the development of new and improved immunotherapy treatments.
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Immune cells grown in dish from pluripotent stem cells
In a world first, researchers have grown immune cells from pluripotent stem cells in a dish, which could be used to develop immunotherapies or to test autoimmune disease treatments.
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New compounds developed to block cancer growth regulator FOXM1
A study has demonstrated the success of new compounds that prevent FOXM1, a transcription factor, from increasing cancer proliferation.
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Study paves way for new vaccines to protect infants against infections
An mRNA vaccine has been developed which has elicited strong immune responses in mice in the presence of maternal antibodies.
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Scientists develop a new way to fight late-stage sepsis
Scientists have used nanotechnology to transform healthy immune cells into a drug with enhanced power to kill bacteria to help the immune system fight sepsis.
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Antibody therapeutic candidate could be used to treat autoimmune diseases
Researchers have used a drug candidate to block a receptor that contributes to the development of autoimmune disease which could be a potential treatment.
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Macrophage response mechanism to pathogens revealed
A study has found the processes used by macrophages in their immune response, which could be used in the development of new vaccines.
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New study could lead to better treatments for autoimmune diseases
A study has found a new molecular process in mice that causes autoimmune diseases and has opened avenues for developing more effective autoimmune therapies.
