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High Throughput Screening (HTS)

Product hub: High-throughput screening of cyclic peptide libraries for developing drugs to challenging targets

28 September 2021 | By BMG Labtech GmbH

Professor Christian Heinis explains how peptides could offer the next generation of therapeutics and what is required to screen libraries of cyclic peptides.

Application note: Streamlined genome engineering in picodroplets

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Application note: Streamlined genome engineering in picodroplets

23 September 2021 | By Sphere Fluidics Ltd.

A picodroplet-based microfluidic method for automating the complete genome-editing workflow. Learn more in this free application note.

Flyer: Introducing Eurofins Beacon Discovery; the GPCR experts

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Flyer: Introducing Eurofins Beacon Discovery; the GPCR experts

17 September 2021 | By Eurofins Discovery

Learn how you can partner for success with Eurofins Beacon Discovery’s industry leading GPCR experts to support your program from concept to clinic.

news

New screening method identifies COVID-19 protein inhibitor

3 September 2021 | By Anna Begley (Drug Target Review)

Researchers use fast and cost-effective technology to identify the viral protein inhibitor Mpro as a potential drug against COVID-19.

news

Record-breaking 3D bioprinter could speed up drug development

16 August 2021 | By Anna Begley (Drug Target Review)

Nanoengineers have developed a high-throughput bioprinter that 3D prints at record speed, potentially accelerating drug development.

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Masitinib found to be an effective COVID-19 treatment in mouse model

3 August 2021 | By Anna Begley (Drug Target Review)

Scientists from the University of Chicago discovered that the drug masitinib inhibits the replication of SARS-CoV-2 in mice.

news

“Untreatable” cases of cystic fibrosis may be undermined by new therapy

28 July 2021 | By Anna Begley (Drug Target Review)

An experimental drug suggests that therapy for currently untreatable cases of cystic fibrosis is “clearly achievable”.

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ebook: High-Throughput Data Management in process development

21 July 2021 | By IDBS

Cell Line Development and cell culture process teams, are you geared up to leverage the vast amount of data generated by high-throughput?

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Screening method finds potential drugs to repurpose against COVID-19

13 July 2021 | By Anna Begley (Drug Target Review)

Researchers have identified 38 drugs that could be repurposed to treat COVID-19 through a strategy involving virtual screening and cell-based assays.

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Mefloquine identified as promising potential drug to combat COVID-19

6 July 2021 | By Anna Begley (Drug Target Review)

Researchers in Japan propose that the antimalarial drug mefloquine could be repurposed to effectively treat SARS-CoV-2.

news

Potential COVID-19 antivirals revealed in large-scale drug analysis

5 July 2021 | By Anna Begley (Drug Target Review)

Drug analysis at the Francis Crick Institute and University of Dundee has revealed 15 potential antivirals that could lead to new COVID-19 treatments.

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Researchers discover class of drugs that could treat mantle cell lymphoma

23 June 2021 | By Victoria Rees (Drug Target Review)

A screening campaign has revealed that small molecule inhibitors of the SOX 11 oncogene are toxic to mantle cell lymphoma in vitro.

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Application note: Pushing the boundaries in pharmaceutical hit discovery with the novel waveRAPID^® kinetic assay

22 June 2021 | By Creoptix

We demonstrate the power of waveRAPID in streamlining the kinetic characterisation of large numbers of drug hit compounds, with results comparable to traditional surface plasmon resonance (SPR) and high reproducibility.

news

Small molecule to potentially treat diabetes discovered in screening study

22 June 2021 | By Victoria Rees (Drug Target Review)

A small molecule found in a cell-based ultra-high-throughput screening campaign was shown to treat diabetes in cells and mice.

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Screening for COVID-19 drugs

22 June 2021 | By Professor Arvind Patel (University of Glasgow)

With the COVID-19 pandemic ongoing, new therapeutic drugs to combat SARS-CoV-2 are still required. In this article, Professor Arvind Patel from the Medical Research Council (MRC) – Centre for Virus Research (CVR) at the University of Glasgow spoke with Drug Target Review’s Victoria Rees to discuss the work being done…

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High Throughput Screening (HTS)