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CRISPR-dCas9 reveals surprising insight into breast cancer development
Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to become abnormal...
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Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
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DNA analysis incorporated into antenatal screening to test for chromosome disorders
Scientists have shown that it is possible to incorporate DNA analysis into antenatal screening for three serious chromosome disorders including Down's syndrome...
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Researchers produce the first draft cell atlas of the small intestine
By surveying gene expression, researchers have created a reference atlas for understanding the biology of inflammatory bowel disease and food allergies, among other conditions...
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SORLA protein protects against Alzheimer’s disease
Researchers have identified a new protective function for a brain protein genetically linked to Alzheimer's...
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Potential new treatment for Fragile X targets one gene to affect many
Inhibitors of chromatin remodelling proteins may be a potential treatment for Fragile X Syndrome...
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Sonic Hedgehog pathway identified as a target against medulloblastoma
Researchers raise hopes for developing a combination targeted therapy to treat medulloblastoma and other tumours...
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Prenatal exposure to BPA at low levels can affect gene expression
Prenatal exposure to BPA affects gene expression related to sexual differentiation and neurodevelopment in the developing brain...
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Computational analysis reveals novel cancer genes
Statistical model pinpoints 27 novel genes thought to prevent cancer from forming...
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CRISPR engineered to edit single RNA letters
New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...
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Alpha-1 antitrypsin deficiency shows promise in rare liver disease
Nuclease-free gene editing has been found to correct mutated cells ...
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Gene transcription in CD8 T cells differentiates chronic from resolving HCV
Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...
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Modified CRISPR technique used to combat Parkinson’s disease
Biological engineers identify genes that protect against protein linked to Parkinson's disease...
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Cell contacts in embryonic development determine cellular fate
Researchers have identified a positive feedback loop between the duration of cell-cell contacts and the specification of a cell's fate...
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Stem cell line offers expanded potential for research and treatments
Researchers have created Expanded Potential Stem Cells that have greater potential for embryonic development than current stem cell lines...
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Underlying genetic causes of congenital heart disease identified
Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...
