Genomics

Scientists control living cells using artificial protein switch

24 July 2019 | By Drug Target Review

Scientists have created the first completely artificial protein switch that can be ‘programmed’ to modify gene expression.

Novel nanoparticles improve CRISPR gene editing

15 July 2019 | By Victoria Rees (Drug Target Review)

A study has used new synthetic lipids to deliver CRISPR gene editing tools into cells with up to 90 percent efficiency.

CRISPR-Cas9 gene editing imaged for first time

9 July 2019 | By Victoria Rees (Drug Target Review)

Researchers have generated images of CRISPR-Cas9 gene editing for the first time, enabling improvement of the technique.

Researchers develop directed evolution technique

8 July 2019 | By Victoria Rees (Drug Target Review)

New method for directed evolution could improve gene therapies and generic drug development.

Next generation molecular medicine: unlocking big data for precision oncology and infectious disease

8 July 2019 | By BASEL Life Science

Join the international [BC]2 conference and EMBO meeting at BASEL LIFE from 9–12 September: a unique opportunity for today’s scientists to get insights and share the latest discoveries, resources and approaches to make sense of genomic and health-related “big data” for molecular medicine – from precision oncology to infectious diseases.

Titian Software Ltd

Potential cure for HIV revealed through combined therapies

3 July 2019 | By Victoria Rees (Drug Target Review)

A new study has used combined therapies to eliminate HIV from mice models, providing potential future cures.

Video: Ethical and regulatory use of biospecimens in the EU

1 July 2019 | By BioIVT

Unique considerations surrounding the bureaucracy and oversight in the use of human biospecimens in the European Union.

Video: Multiplex IHC and digital analysis for immuno-oncology

1 July 2019 | By BioIVT

High content data derived for complex immuno-oncology research facilitates a deeper understanding of the tissue microenvironment.

Longest successful gene expression raises hopes for gene editing therapies

20 June 2019 | By Victoria Rees (Drug Target Review)

A study has reported that genes delivered to rhesus monkeys are still being expressed four years later.

Lyme arthritis molecule found, providing treatment opportunity

20 June 2019 | By Victoria Rees (Drug Target Review)

A new study has identified a key molecule involved in Lyme arthritis which presents options for preventative therapies.

New technology provides process for precise gene editing

13 June 2019 | By Victoria Rees (Drug Target Review)

Researchers have presented their new technology for accurately inserting genes into the genome without cutting DNA.

CRISPR/Cas9-engineered cancer models: the next step forward for targeted cancer therapy

11 June 2019 | By Elizabeth Turner Gillies PhD, Fang Tian PhD

The advent of CRISPR/Cas9 gene editing, together with the plummeting cost of whole-genome sequencing, has cleared a path for the development of customised cancer cell models. Here, we discuss recent developments in the field and challenges associated with targeted-therapy resistance.

Whitepaper: Cubis^® II pharma compliant by design

6 June 2019 | By Sartorius AG

Sartorius Cubis® II is designed to follow US FDA data integrity principles that require data to be accurate, legible, contemporaneous, original and attributable.

‘CRISPR babies’ may have shorter life expectancy

6 June 2019 | By Drug Target Review

A study of almost half a million people links a mutation that protects against HIV infection to an earlier death.