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ANT1 mutation links bipolar disorder to mitochondrial disease
Researchers have reported that mitochondrial dysfunction affects the activity of serotonergic neurons in mice with mutations of ANT1...
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Genetic analysis
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Profiling the genome hundreds of variations at a time
A CRISPR-Cas9 high-throughput strategy creates the possibility to rapidly profile and identify genes and DNA sequence variations key to different traits and diseases.
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Cell types underlying schizophrenia identified
Scientists have identified the cell types underlying schizophrenia, the findings offer a roadmap for the development of new therapies to target the condition...
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NDF identified as the missing factor in gene activation
Scientists find the missing factor in gene activation...
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Sequencing offers clues to progression toward multiple myeloma
Researchers have carried out the largest genomic analysis of patients with SMM to explain the biology of the disease and how it unfolds through time...
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Leukaemia protective role of Y chromosome gene discovered
Scientists have discovered the first leukaemia protective gene that is specific to the male-only Y chromosome...
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Genomic analysis unravels complexities of the most common form of lymphoma
Genomic analysis has shown a better framework for understanding lymphoma’s many forms and will help to predict individual patient outcomes and guide personalised treatment.
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New insights into the origins of mutations in cancer
Scientists use data from human cancers and C. elegans to understand mutational causes of cancer...
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Genetic catalyst identifies the evolution of antibiotic resistance
Researchers have shown that it is possible to identify genetic catalysts that accelerate the evolution of antibiotic resistance in bacteria...
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Scientists mine gene responses to existing chemotherapies to facilitate precision cancer treatment
Scientists utilise computational biology techniques in a bid to enable doctors to use targeted therapies for cancer patients.
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Scientists find that dectin-1 receptor protects against allergies
Contrary to previous notions that the receptor dectin-1 causes allergic reactions, new research from the John Hopkins Bloomberg School of Public Health has found that it actually prevents this response, indicating new targets for allergy and asthma drugs.
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New machine learning algorithm uncovers time-delayed interactions in cells
Scientists have designed a new machine learning algorithm that uses time-series data to uncover underlying biological networks.
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Harnessing the power of genomic sequencing augments diagnosis and treatment of lymphoid cancer
A new study has established that hybrid-capture sequencing is the method of choice for sequencing “actionable” gene mutations across the most common forms of lymphoid cancer.
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New body of resistance gene research has potential to combat superbugs
Scientists in Denmark have made it possible to rank the risk of resistance genes and predict the evolution of existing and future drugs.
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Precise genetic cause of rare hypertension syndrome is discovered
Scientists at the Berlin Institute of Health have discovered how mutations in a new disease gene CLCN2 cause the unusual inherited form of high blood pressure: Familial hyperaldosteronism type II.
