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Researchers in the states have discovered a particular gene mutation that slows down sugar metabolism in the gut, indicating future treatment options for individuals with cardiometabolic and sugar-associated diseases.
Researchers show the first example of a base-editing tool to treat a disease in utero in animal models...
Researchers have found another common thread linking nearly all of the TNR expansion diseases...
GABAA receptors represent a large and complicated family of ion channels that consist of at least 16 subunits (α1-6, β1-3, γ1-3, δ, ε, π, θ) that have been shown to be vital for the normal functioning of the brain. These inhibitory ligand-gated channels have been shown to beimportant in sedation,…
Researchers have determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation...
Researchers have adapted CRISPR to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building...
A specific haplotype was identified as having the highest risk of development, with another showing the lowest risk...
Blindness in children has been linked to a recessive genetic disorder caused by the MARK3 gene...
Kidneys are crucial for filtration of drugs and toxins and their proper function is essential for overall health. Unfortunately, due to disease and improper function, kidney transplantation or dialysis are necessary for millions of patients annually all over the world.1,2
In an experiment with pigs, researchers have demonstrated for the first time that the administration of even extremely low doses of an endocrine disruptor - in this case, an endogenous oestrogen - leads to epigenetic changes in a pregnant sow’s DNA.
A team of researchers have identified four different mutations in the gene TRAF7...
Scientists are a step closer to understanding which genes are responsible for early-onset Alzheimer's disease in people with Down syndrome...
A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin.
Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies...
