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Gene Therapy is the introduction of normal genes into cells in place of missing or defective ones in order to correct genetic disorders.
Research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs...
Gene therapy has been used to restore hearing in an adult mouse model of DFNB9 deafness, one of the most frequent cases of congenital genetic deafness...
Drug target identification has a key role in the drug discovery value chain. A critical step in the development of pharmaceuticals is identifying the direct targets of potential drug candidates as well as distinguishing any secondary or off-target effects...
Reporter gene assays have greatly helped our understanding of gene regulation and signal transduction in vitro and in vivo.
A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy...
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases...
6 September 2018 | By Takara Bio
The data presented in this application note demonstrates how SMARTer ICELL8 Single-Cell System can be used to generate high-quality RNA-seq libraries that provide full-length transcript sequence information from hundreds of single cells in parallel...
Scientists in the U.S. have demonstrated an effective means of administering gene therapy in mice, without the dangerous autoimmune reaction that often occurs.
A new molecular imaging method can monitor the success of gene therapy in all areas of the brain, potentially allowing physicians to more effectively address brain conditions such as Parkinson's disease, Alzheimer's disease and multiple sclerosis.
Progress in stem cell research and its translation to medicine is the focus of the International Society for Stem Cell Research annual meeting 20-23 June at the Melbourne Convention & Exhibition Centre in Melbourne, Australia.
Target the genes that matter for efficient sequencing and analysis with custom-targeted gene panels.
Predictiveness is one of the key factors for success in the drug discovery workflow. Many compounds fail at late stages due to lack of predictive data or the discovery of unwanted side effects.
The 13th annual World Advanced Therapies & Regenerative Medicine Congress brings together 1000+ attendees and explores the rapidly developing world of next generation therapeutics and ATMPS.
Presenting issues and real-life examples within the RNA space, SMi welcome insights and discussions into new technologies for single-stranded RNA, epigenetics to develop first-in class drugs in oncology, patenting RNA Therapeutics and exploring the latest developments in delivery systems, including Exosomes and Nanocomplexes. Read on for your exclusive discount to…
Scientists have rebuilt adenoviruses so that they effectively recognise and infect tumour cells.
