news
New potential liver cancer treatment found with biomarker-guided strategy
A cellular pathway may reduce side effects and extend immunotherapy duration in patients with the most common form of liver cancer.
List view / Grid view
Enzymes
Enzymes are macromolecular biological catalysts. Enzymes accelerate, or catalyse, chemical reactions.
news
RNA editing capabilities expanded with new CRISPR platform
A research team have developed a new CRISPR platform called RESCUE (RNA Editing for Specific C to U Exchange).
news
Secondary structures study could lead to making cancer cells vulnerable
Researchers have used machine learning to discover that the two most widespread DNA structures cause genome mutations that lead to cancer.
news
Researchers reverse prediabetes in mice through enzyme deactivation
A study has shown that deactivating an enzyme linked to ceramides caused obese mice to improve their metabolic health, indicating a drug target.
news
Research shows pancreatitis biomarker linked to pancreatic cancer
A study has discovered that a biomarker associated with pancreatitis is involved in its development to pancreatic cancer.
news
Scientists have discovered important redundancies in T cells
Redundancies have been discovered in the biochemical signalling pathways of immune cells which could impact cancer immunotherapy.
news
Study identifies two enzymes which protect tumour cells
Researchers have found an enzyme and its counterpart which inhibit T-cells from attacking tumour cells.
news
Autoimmune disorders could be treated with new compounds
New research could lead to novel treatments for autoimmune disorders and sheds light on the causes of autoimmunity.
news
Scientists decipher 3D structure of promising molecular target for cancer treatment
Columbia University discovery could be a major step in developing therapies for cancer, controlling cholesterol...
news
Therapeutic strategy to prevent gastrointestinal disease
New approach restores epithelial function in diarrhoea and inflammatory bowel disease models...
news
GREB1 gene potential drug target for prostate cancer treatment
Researchers in the US have discovered how a gene involved in regulating hormone receptors, GREB1, may contribute to drug resistance in some prostate cancer patients.
news
New imaging tools that trace key breast cancer enzymes may help guide therapies
Series of molecules may provide more reliable relief with fewer side effects...
whitepaper
Application note: A novel solution to expedite antibody discovery
With breakthroughs in molecular engineering and antibody humanisation, monoclonal antibodies (mAb) are one of the fastest-growing classes of biopharmaceuticals for multiple clinical indications including cancer, cardiovascular disease, autoimmune disorders and infectious disease. Most therapeutic antibody candidates are initially generated using hybridoma technology or primary B-cell screening after antigen immunisation.
news
Heat-resistant enzymes for cost-effective drugs
The mechanisms and actions of heat-resistant enzymes are being investigated to aid better, more cost-effective drug design...
webinar
Integrated fragment-based approach reveals enzymatic inhibitors with potential therapeutic application
25 October 2018 | By NanoTemper Technologies
In this webinar, speakers presented results of integrated fragment-based approaches that have led to the discovery of the first ligands of IDO1 that are able to modulate non-catalytic signalling functions of the enzyme...
