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New class of drugs could help tackle treatment-resistant cancers
Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies...
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Study develops compound that activates tumour-fighting iNKT cells
Researchers have discovered a significant new compound that helps to mobilise a type of T cell – invariant natural killer T (iNKT) cells – in the fight against disease.
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I-BET-762 may stop cancer-causing gene in its tracks
Scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer...
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Medicinal cannabis is safe and effective — it’s time to reboot research
Researchers claim that medicinal cannabis is safe and effective for pain relief, and are calling for the treatment to be properly established in our modern medical arsenal...
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Three-in-one molecule shows promise in helping certain breast cancer patients
A newly designed three-part molecule could be the one answer patients with a certain form of breast cancer are looking for...
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Researchers identify compound to prevent breast cancer cells from activating in brain
Researchers have used computer modelling to find an existing investigational drug compound for leukaemia patients to treat triple negative breast cancer...
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Scientists identify genes that could develop therapies for EBV-related cancers
Researchers have identified two genes that are responsible for governing the replication of the Epstein-Barr virus, an infection that drives the growth of several types of cancer...
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Microglia in the retina can spontaneously regenerate
NIH discovery in mice could lead to therapies to reduce vision loss from diseases of the retina...
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CIS43 antibody prevents malaria in mice
Scientists have discovered a human antibody that protected mice from infection with the deadliest malaria parasite, Plasmodium falciparum...
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PARK14 protein associated with inflammation in Parkinson’s
Study overturns previous ideas about enzyme linked to many illnesses
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Informatics In-Depth Focus 2018
In this In-Depth Focus: enabling research on understudied and unstudied targets, and using multi-omics data to detail drug responses in the human metabolic network.
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CRISPR-based system identifies drug targets in AML
Scientists have discovered a way to rein in an overactive protein that drives some aggressive leukaemias...
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Combination therapy suppresses HIV-like virus in primates
Broadly neutralising antibody treatment may target viral reservoir in monkeys...
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Kenpaullone protects from cisplatin-induced hearing loss
Researchers have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 protects mice and rats from noise- or drug-induced hearing loss...
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Blockade of MT4-MMP protease increases blood-patrolling monocyte activity
Researchers in Spain have identified a function of the MT4-MMP protease (an enzyme that breaks down proteins) that could be targeted as a potential treatment for some infections, as well as tumour metastasis.
