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Cancer cells hide to evade immunotherapy
Cancer cells have been found to evade immunotherapy by hiding behind human leukocyte antigens, with researchers identifying therapies to prevent relapse...
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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A universal flu vaccine may be in sight
Researchers from Oxford have identified the initial steps on the path towards creating a universal influenza vaccine that could last for life...
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Amyloid beta – a good therapeutic target?
Phase III clinical trials for a drug targeting amyloid beta plaques are underway, with results expected in the next two to three years...
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Np63a should be targeted in squamous cell carcinomas
A team of researchers have identified that to target p63, both TGFB2 and RHOA tumour suppressor genes should be activated...
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Structural map of bacterial toxins identified
A three-dimensional structural map of bacterial toxins has been identified for the bacterium Pseudomonas aeruginosa...
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Six compounds identified from 70,000 to help eradicate malaria
Researchers from Imperial College London have identified 6 compounds from almost 70,000 that could help to eradicate malaria...
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Fewer side effects from cancer drugs promised
Researchers from Copenhagen have developed a method of accurately using proteins to track the path of a drug through the body to ensure its safety...
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Disrupting genetic processes reverses ageing in human cells
Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age...
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Synthetic biology in drug discovery
Synthetic biology is broadly defined as the design and construction of novel artificial biological pathways, organisms or devices; or the redesign of existing natural biological systems.1 It brings together a range of disciplines and skills, from biology and chemistry to computing, bioinformatics and engineering.
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Targeting mitochondria could reduce cancer invasiveness and resistance to radiotherapy
Uncovered details of a molecular pathway in cancer cells could lead to improved treatment...
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CypA enzyme found in breast milk identified as a target for novel breast cancer drugs
Researchers have identified a protein involved in milk production that could ultimately serve as a target for novel therapies to treat breast cancer...
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Hsp90: Not just a chaperone
Researchers have shown that heat-shock protein 90 acts as a stimulant for exosome release, as well as a protein chaperone...
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Non-antibiotic drug developed to treat TB
Scientists at The University of Manchester have developed the first non-antibiotic drug to successfully treat tuberculosis in animals...
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Tau protein disrupts molecular transport in neurons in Alzheimer’s
Researchers have discovered how the tau protein associated with Alzheimer's affects molecular transport and a nucleporin called Nup98...
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Neutrophil nanosponges soak up rheumatoid arthritis promoting proteins
The neutrophil nanosponges can absorb and neutralise cytokines which play a role in the development of rheumatoid arthritis...
