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Tissue-damaging protein channel identified
Researchers have discovered an acid-activated protein which could stop damage to tissues as a result of stroke and other health issues.
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Cancer-killing combination therapies unveiled with new drug-screening tool
Method IDs which target therapies, inadequately on their own, can be paired up to kill non-responsive cancers...
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New cancer drug targets accelerate path to precision medicine
Researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival...
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MicroRNA regulates drug tolerance in subset of lung cancers
Newly identified pathway offers promising targets for preventing tumour relapse...
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Cancer vaccine shows promising results in Lynch syndrome
Vaccination with as few as four tumour antigens generated antigen-specific responses, reduced intestinal tumours, and improved survival in a mouse model of Lynch syndrome...
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Machine-learning model to analyse protein sequences
A machine-learning model has been developed to analyse protein sequences, giving an insight to their structure, function and phylogeny...
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Salamander gene partnerships could help spinal cord regeneration
Gene partnerships found in salamander could give insights into how spinal cord injuries and neurodegenerative conditions could be better treated...
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Anthelmintic drug niclosamide repurposed to treat Helicobacter pylori
Researchers have repurposed use of niclosamide to treat Helicobacter pylori cell lines, focusing on how it is effective in infection models...
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Genetic study confirms that numerous genes contribute to Tourette’s syndrome
A meta-analyses of a number of studies has found that variants in numerous genes work together to contribute to Tourette's syndrome...
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Secret life of antimicrobial peptide revealed through CRISPR
Antimicrobial peptides were found to act against Gram-negative bacteria and certain fungi by working either together or by adding up their individual effects...
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Book mechanism identified as communication method for bacterial toxins
Researchers have identified the mechanism by which highly toxic compounds communicate, and how they use vesicles to be transported...
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MRI sensor to image activity deep inside the brain
A method of imaging calcium activity that is based on magnetic resonance imaging (MRI) could help to image deep within the brain...
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Taking a BiTE out of lung cancer
Bispecific T-cell engager technology (BiTE) could be used to quickly and accurately diagnose patients suffering from lung cancer...
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Gene therapy to reduce deafness in mice
Gene therapy has been used to restore hearing in an adult mouse model of DFNB9 deafness, one of the most frequent cases of congenital genetic deafness...
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Fighting HIV using anti-cancer immunotherapy
Researchers have used immunotherapy treatments, ordinarily used to treat cancer, to reveal the virus in the cells of people living with HIV...
