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Despite being one of the more ancient aspects of immunity, therapeutic modulation of the innate immune system has rarely been attempted. Innate immunity is intrinsically linked to the generation of inflammation – necessary for signalling to the adaptive immune system but often self-perpetuating and over-exaggerated, leading to deleterious effects, including…
The discovery of a new gene in zebrafish could lead to a better understanding of how exposure to chemicals leads to disease in humans...
Scientists in the U.S. have developed molecules, termed cyclic peptoids, that block the action of genes that drive the growth of therapy-resistant prostate cancer, according to a new study.
Women with ovarian cancer could in future benefit from a combined therapy using PD-1 and CTLA-4 as shown through the results of this Phase II trial...
Researchers from Imperial College London have identified 6 compounds from almost 70,000 that could help to eradicate malaria...
Researchers have developed a new generation of pain relief drugs that only target the affected area, with the help of computer simulations...
The compound has been shown to target cancer cells without the p53 gene, and does not affect healthy cells...
Researchers have discovered that FFW and Sorafenib used together could reduce the growth of Sorafenib resistant hepatocellular carcinoma tumours...
Many biopharmaceutical companies look to produce biosimilars soon, since the patents on the original mAb expire over the next few years...
Mice with pancreatic cancer that were treated with CBD alongside chemotherapy, survived almost three times longer than those treated with chemotherapy alone...
Researchers have conducted promising preclinical experiments on a compound that could be used to treat Wilson's disease...
A new study has shown that an experimental drug known as AZ32 significantly extends the survival of glioblastoma multiforme, the most common and deadly form of brain cancer...
Scientists in the Netherlands have investigated the structure of the human glutamine transporter ASCT2 in a bid to generate leads for cancer drug development.
Scientists have investigated the mechanisms by which the lymphatic endothelial cells modulate metastasis in melanoma, providing new targets for therapy development.
Scientists in the U.S. have reported that an experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can often continue months after a person has suffered the stroke.
